EGF/FGF/PDGF receptor tyrosine kinase inhibitor

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Names

[ Name ]:
EGF/FGF/PDGF receptor tyrosine kinase inhibitor

[Synonym ]:
1-(2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butyl urea
PDGFR Tyrosine Kinase Inhibitor XIII
PD 089828
Urea, N-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-
1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
1-[2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-(2-methyl-2-propanyl)urea

Chemical & Physical Properties

[ Density]:
~1.4 g/cm3(Predicted)

[ Boiling Point ]:
594.56° C (Predicted)

[ Melting Point ]:
256.77° C (Predicted)

[ Molecular Formula ]:
C₁₈H₁₈Cl₂N₆O

[ Molecular Weight ]:
405.28

[ Exact Mass ]:
404.091919

[ LogP ]:
2.12

[ Index of Refraction ]:
n20D1.69 (Predicted)

[ Water Solubility ]:
Soluble in DMSO (25 mg/ml), and ethanol (1 mg/ml).

Safety Information

Related Compounds

(5-BUTANOATE-1H-2-INDOLYL)(1H-2-INDOLYL)-METHANONE
(5-hydroxy-1H-indol-2-yl)-(1H-indol-2-yl)methanone
PDGFR Tyrosine Kinase Inhibitor III
JNJ-10198409
N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE
KRN-633
3,4-Dimethyl-2-(2-nitroethenyl)thiophene
(5S)-1-Benzoyl-5-methoxy-2-pyrrolidinone
4-(Diphenylmethylene)proline ethyl ester
L-Tyrosine, 2-bromo-O-(trifluoromethyl)-
5-(3-Hydroxy-4-methylphenyl)-1,3-oxazolidin-2-one
2-Methyl-7-nitro-1H-indole-3-acetic acid
2-Fluoro-4-(3-methyl-2-quinolinyl)phenol
3-Amino-4-(3-phenoxyphenyl)butanoic acid
4-(2-Benzoxazolyl)-3-hydroxybenzonitrile
6-Nitro-1H-benzimidazole-2-nonanoic acid