E-4031

Suppliers

Names

[ Name ]:
E-4031

[Synonym ]:
Methanesulfonamide, N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]-, hydrochloride (1:2)
N-[4-({1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl}carbonyl)phenyl]methanesulfonamide dihydrochloride
E-4031
N-(4-(1-(2-(6-methylpyridin-2-yl)ethyl)piperidine-4-carbonyl)phenyl)methanesulfonamide dihydrochloride
N-[4-({1-[2-(6-Methylpyridin-2-yl)ethyl]piperidin-4-yl}carbonyl)phenyl]methanesulfonamide dihydrochloride
MFCD01754739
E 4031 dihydrochloride
PDZ1 Domain inhibitor peptide

Chemical & Physical Properties

[ Boiling Point ]:
561.7ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₉Cl₂N₃O₃S

[ Molecular Weight ]:
474.444

[ Flash Point ]:
293.5ºC

[ Exact Mass ]:
473.130676

[ PSA ]:
87.75000

[ LogP ]:
5.59460

[ Vapour Pressure ]:
1.21E-12mmHg at 25°C

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Kcnh2 and Kcnj8 interactively regulate skin wound healing and regeneration.

Wound Repair Regen. 23 , 797-806, (2015)

Previous studies indicate that ion channels are mediators of bioelectricity promoting wound closure/regeneration in nonmammalian, lower vertebrate systems. The role of ion channels however in regenera...

Direct negative chronotropic action of desflurane on sinoatrial node pacemaker activity in the guinea pig heart.

Anesthesiology 120(6) , 1400-13, (2014)

Desflurane inhalation is associated with sympathetic activation and concomitant increase in heart rate in humans and experimental animals. There is, however, little information concerning the direct e...

Bridging Functional and Structural Cardiotoxicity Assays Using Human Embryonic Stem Cell-Derived Cardiomyocytes for a More Comprehensive Risk Assessment.

Toxicol. Sci. 148 , 241-60, (2015)

More relevant and reliable preclinical cardiotoxicity tests are required to improve drug safety and reduce the cost of drug development. Current in vitro testing strategies predominantly take the form...

(E,E)-2-<(4-methoxyphenyl)methylene>-3-(2-thienylmethylene)succinic anhydride
(E)-β-acetylvinyl phenyl sulphone
(E)-ALPHA-(4-CHLOROPHENYL)CINNAMONITRILE
(E)-5-benzylidene-3-ethoxycarbonyl-4-hydroxyfuran-2(5H)-one
(E)-N-[(E)-propylideneamino]propan-1-imine
(E)-N'-((1H-indol-3-yl)methylene)-3-((3,5-dihydroxy-1,2,4-triazin-6-yl)amino)propanehydrazide
2-(3,4-Dihydroxyphenyl)-3-methylbutanoic acid
3-Amino-5,5-dimethylpyrrolidin-2-one
3-Ethyl-5-methoxy-4-methylphenol
3-amino-3-{4H,5H,6H-cyclopenta[b]thiophen-2-yl}propanoic acid
5-Bromo-3,4-dihydro-8-methoxyisoquinoline
3-(1H-indol-3-yl)-2,2-dimethylcyclopropane-1-carboxylic acid
N-(3-Chloro-4-methoxyphenyl)thietan-3-amine
2-(Trifluoromethyl)-1-benzofuran-3-carboxylic acid
1-(2,3-dihydro-1H-inden-5-yl)-2,2-dimethylcyclopropane-1-carboxylic acid
1-isobutyl-3-(pyridin-2-yl)-1H-pyrazol-5-amine

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