Cyclohexylacetyl-Phe-Arg-Ser-Val-Gln-NH2 trifluoroacetate salt

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Names

[ CAS No. ]:
113584-01-3

[ Name ]:
Cyclohexylacetyl-Phe-Arg-Ser-Val-Gln-NH2 trifluoroacetate salt

[Synonym ]:
kallikrein inhibitor peptide
kki-7
cyclohexylacetyl-phe-arg-ser-val-gln amide

Chemical & Physical Properties

[ Density]:
1.39g/cm3

[ Molecular Formula ]:
C36H58N10O8

[ Molecular Weight ]:
758.90800

[ Exact Mass ]:
758.44400

[ PSA ]:
313.81000

[ LogP ]:
2.83190

[ Index of Refraction ]:
1.637

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

In vivo inhibition of tissue kallikreins by kininogen sequence analogue peptides.

Adv. Exp. Med. Biol. 247B , 23-28, (1989)

Kininogen sequence analogs containing amino acid residues around the Arg-Ser cleavage site of bovine kininogens were prepared with bulky aliphatic residues in P3 position. KKI-7 (containing a cyclohex...

The design of specific inhibitors of tissue kallikrein and their effect on the blood pressure of the rat.

Adv. Exp. Med. Biol. 247B , 9-13, (1989)

Prolonged kallikrein inhibition does not affect the basal growth and secretory capacity of rat adrenal cortex, but enhances mineralo- and glucocorticoid response to ACTH and handling stress.

Histol. Histopathol. 15(2) , 441-4, (2000)

The effects on the pituitary-adrenocortical functions of the prolonged (7-day) blockade of endogenous bradykinin (BK) synthesis, obtained by the administration of the kallikrein inhibitor (K-I) cycloh...


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