Phenylac-Gly-Lys-OH

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Names

[ CAS No. ]:
113969-25-8

[ Name ]:
Phenylac-Gly-Lys-OH

[Synonym ]:
6-amino-2-[[2-[(2-phenylacetyl)amino]acetyl]amino]hexanoic acid

Chemical & Physical Properties

[ Molecular Formula ]:
C16H23N3O4

[ Molecular Weight ]:
321.37200

[ Exact Mass ]:
321.16900

[ PSA ]:
121.52000

[ LogP ]:
1.52580

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody.

J. Biol. Chem. 280 , 22154-22164, (2005)

Tryptophan can be oxidized in the eye lens by both enzymatic and non-enzymatic mechanisms. Oxidation products, such as kynurenines, react with proteins to form yellow-brown pigments and cause covalent...

Elucidation of a novel polypeptide cross-link involving 3-hydroxykynurenine.

Biochemistry 38 , 11455-11464, (1999)

3-Hydroxykynurenine, a metabolite of tryptophan, is a powerful antioxidant and neurotoxin. The neurotoxicity results from the oxidation of 3-hydroxykynurenine, and hydroxyl radicals, formed via H(2)O(...

Polypeptide modification and cross-linking by oxidized 3-hydroxykynurenine.

Biochemistry 39 , 16176-16184, (2000)

3-Hydroxykynurenine (3OHKyn) is present in the mammalian lens as a UV filter and is formed from kynurenine in the tryptophan metabolic pathway. 3OHKyn is a readily autoxidized o-aminophenol which bind...


More Articles


Related Compounds

  • H-Gly-Lys-OH · HCl
  • H-Lys-Gly-Lys-OH acetate salt
  • H-Lys-Phe-Gly-Lys-OH acetate salt
  • H-Pro-Phe-Gly-Lys-OH acetate salt
  • H-Lys-Trp-Gly-Lys-OH
  • Hippuryl-Lys-OH