PHACLOFEN

Suppliers

Names

[ CAS No. ]:
114012-12-3

[ Name ]:
PHACLOFEN

[Synonym ]:
3-Amino-2-(4-chlorophenyl)propanephosphonic acid
MFCD00069328

Chemical & Physical Properties

[ Density]:
1.432 g/cm3

[ Boiling Point ]:
467.1ºC at 760 mmHg

[ Molecular Formula ]:
C9H13ClNO3P

[ Molecular Weight ]:
249.63100

[ Flash Point ]:
236.3ºC

[ Exact Mass ]:
249.03200

[ PSA ]:
93.36000

[ LogP ]:
2.26030

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Chloro-β-nitrostyrene
  • Dimethyl 2-(4-chlorophenyl)-3-nitropropylphosphonate
  • 3-(4-chlorophenyl)-4-phosphonobutanoic acid

DownStream

Articles

PKC-mediated GABAergic enhancement of dopaminergic responses: implication for short-term potentiation at a dual-transmitter synapse.

J. Neurophysiol. 112(1) , 22-9, (2014)

Transmitter-mediated homosynaptic potentiation is generally implemented by the same transmitter that mediates the excitatory postsynaptic potentials (EPSPs), e.g., glutamate. When a presynaptic neuron...

Transcriptome analysis of the key role of GAT2 gene in the hyper-accumulation of copper in the oyster Crassostrea angulata.

Sci. Rep. 5 , 17751, (2015)

One paradigm of oysters as the hyper-accumulators of many toxic metals is the inter-individual variation of metals, but the molecular mechanisms remain very elusive. A comprehensive analysis of the tr...

The antinociceptive effect of stimulating the retrosplenial cortex in the rat tail-flick test but not in the formalin test involves the rostral anterior cingulate cortex.

Pharmacol. Biochem. Behav. 131 , 112-8, (2015)

The stimulation of the retrosplenial cortex (RSC) is antinociceptive in the rat tail-flick and formalin tests. The rat RSC is caudal to and send projections to the ipsilateral anterior cingulate corte...


More Articles

Related Compounds

  • Phaclofen
  • 8-[(dibenzylamino)methyl]-1,3-dimethyl-7-pentyl-5H-purin-7-ium-2,6-dione
  • ethyl 4-[(1,3-dimethyl-2,6-dioxo-7-phenacyl-5H-purin-7-ium-8-yl)methyl]piperazine-1-carboxylate
  • 8-[[4-(3-Chlorophenyl)piperazin-1-yl]methyl]-3-methyl-7-(2-methylpropyl)-4,5-dihydropurine-2,6-dione
  • 5-(trifluoroacetyl)-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-6-carboxylic acid
  • 1-Pyrimidin-4-yl-1h-pyrazole-4-carbaldehyde
  • N-(6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)benzofuran-2-carboxamide
  • 8-[(Dibenzylamino)methyl]-1,3-dimethyl-7-(2-phenylethyl)-4,5-dihydropurine-2,6-dione
  • 7-(2-ethoxyethyl)-8-[[4-(2-fluorophenyl)piperazin-1-yl]methyl]-1,3-dimethyl-5H-purin-7-ium-2,6-dione
  • 6-(4-Methylphenyl)piperidin-2-one
  • tert-Butyl (3R)-3-(((4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl)carbonyl)-6,6,6-trifluorohexanoate
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