PHACLOFEN

Suppliers

Names

[ CAS No. ]:
114012-12-3

[ Name ]:
PHACLOFEN

[Synonym ]:
3-Amino-2-(4-chlorophenyl)propanephosphonic acid
MFCD00069328

Chemical & Physical Properties

[ Density]:
1.432 g/cm3

[ Boiling Point ]:
467.1ºC at 760 mmHg

[ Molecular Formula ]:
C9H13ClNO3P

[ Molecular Weight ]:
249.63100

[ Flash Point ]:
236.3ºC

[ Exact Mass ]:
249.03200

[ PSA ]:
93.36000

[ LogP ]:
2.26030

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Chloro-β-nitrostyrene
  • Dimethyl 2-(4-chlorophenyl)-3-nitropropylphosphonate
  • 3-(4-chlorophenyl)-4-phosphonobutanoic acid

DownStream

Articles

PKC-mediated GABAergic enhancement of dopaminergic responses: implication for short-term potentiation at a dual-transmitter synapse.

J. Neurophysiol. 112(1) , 22-9, (2014)

Transmitter-mediated homosynaptic potentiation is generally implemented by the same transmitter that mediates the excitatory postsynaptic potentials (EPSPs), e.g., glutamate. When a presynaptic neuron...

Transcriptome analysis of the key role of GAT2 gene in the hyper-accumulation of copper in the oyster Crassostrea angulata.

Sci. Rep. 5 , 17751, (2015)

One paradigm of oysters as the hyper-accumulators of many toxic metals is the inter-individual variation of metals, but the molecular mechanisms remain very elusive. A comprehensive analysis of the tr...

The antinociceptive effect of stimulating the retrosplenial cortex in the rat tail-flick test but not in the formalin test involves the rostral anterior cingulate cortex.

Pharmacol. Biochem. Behav. 131 , 112-8, (2015)

The stimulation of the retrosplenial cortex (RSC) is antinociceptive in the rat tail-flick and formalin tests. The rat RSC is caudal to and send projections to the ipsilateral anterior cingulate corte...


More Articles


Related Compounds

  • Phaclofen
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 8-Oxa-4-thia-3,5,6-triazadecanoic acid, 9,9-dimethyl-7-oxo-, 4,4-dioxide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide