R-Fluoxetine hydrochloride

Suppliers

Names

[ Name ]:
R-Fluoxetine hydrochloride

[Synonym ]:
(3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine,hydrochloride
(R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride
MFCD04040065
R-(−)-Fluoxetine hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
395.1ºC at 760 mmHg

[ Melting Point ]:
126-129°C

[ Molecular Formula ]:
C₁₇H₁₉ClF₃NO

[ Molecular Weight ]:
345.78700

[ Exact Mass ]:
345.11100

[ PSA ]:
21.26000

[ LogP ]:
5.62790

[ Appearance of Characters ]:
solid | white

[ Vapour Pressure ]:
1.88E-06mmHg at 25°C

[ Storage condition ]:
Hygroscopic, -20?C Freezer, Under Inert Atmosphere

[ Water Solubility ]:
H2O: 20 mg/mL, soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22;R38;R41

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Iodobenzotrifluoride
( R)-3-(Methylamino)-1-phenylpropanol
Fluoxetine
(+)-N-tert-butoxycarbonyl-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propanamine
4-Chlorobenzotrifluoride
methylamine
[R]-(+)-1-chloro-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propane
3-(dimethylamino)-1-phenylpropan-1-one

DownStream

Articles

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

Benzyl-d5 Bromide
(R)-Fluoxetine-d5 Hydrochloride
(R)-fluoxetine
meta-Fluoxetine (hydrochloride)
S-(+)-FLUOXETINE HYDROCHLORIDE
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine,N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine,hydrochloride
N-(4-butoxyphenyl)-3-(3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboxamide
N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-3-methoxy-1-methyl-1H-pyrazole-4-carboxamide
N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-5-(furan-2-yl)isoxazole-3-carboxamide
1-methyl-2-oxo-N-(2-(1-tosylpiperidin-2-yl)ethyl)-1,2-dihydropyridine-3-carboxamide
5-chloro-N-(2-(1-(thiophen-2-ylsulfonyl)piperidin-2-yl)ethyl)thiophene-2-carboxamide
N1-(1-(methylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)-N2-(2-morpholino-2-(thiophen-2-yl)ethyl)oxalamide
1-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)ethan-1-one
N1-(2-(dimethylamino)-2-(p-tolyl)ethyl)-N2-(2,2,2-trifluoroethyl)oxalamide
4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
1-Fluoro-5-(2-fluorophenyl)naphthalene

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