Capivasertib (AZD5363)

Suppliers

Names

[ Name ]:
Capivasertib (AZD5363)

[Synonym ]:
4-Piperidinecarboxamide, 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-
4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(1H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxamide
cc-638
AZD5363
UNII-WFR23M21IE
CS-1284
AZD-5363

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₂₁H₂₅ClN₆O₂

[ Molecular Weight ]:
428.915

[ Exact Mass ]:
428.172760

[ PSA ]:
123.65000

[ LogP ]:
1.04

[ Index of Refraction ]:
1.670

[ Storage condition ]:
-20℃

Safety Information

[ Hazard Codes ]:
Xn

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)piperidine-4-carboxamide
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
(S)-tert-butyl 4-(1-(4-chlorophenyl)-3-hydroxypropylcarbamoyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-ylcarbamate
(3S)-3-amino-3-(4-chlorophenyl)propanoic acid
N-boc-amino-piperidinyl-1,1-carboxylic acid