3'-deoxy-5'-o-(dimethoxytrityl)-5-methyluridine

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Names

[ CAS No. ]:
114551-15-4

[ Name ]:
3'-deoxy-5'-o-(dimethoxytrityl)-5-methyluridine

Chemical & Physical Properties

[ Molecular Formula ]:
C31H32N2O7

[ Molecular Weight ]:
544.59500

[ Exact Mass ]:
544.22100

[ PSA ]:
112.01000

[ LogP ]:
3.51930

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4,4'-Dimethoxytrityl chloride
  • 1-[(2R,3S,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 5-Methyluridine
  • 1,2-di-O-acetyl-5-O-(methoxycarbonyl)-3-deoxy-D-erythro-pentofuranose
  • ((2S,4R,5R)-4-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl methyl carbonate
  • 1-(2-O-acetyl-3-deoxy-5-O-methoxycarbonyl-β-D-erythro-pentofuranosyl)thymine
  • bis(o-trimethylsilyl)thymine

DownStream

  • 1-[(2R,3S,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Related Compounds

  • 3'-deoxy-5'-O-dimethoxytrityl-5-methyluridine
  • 3'-Deoxy-5'-O-(4-methoxyphenyl)-3'-methylidene-β-D-thymidine
  • 3'-O- acetyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methyluridine
  • 2'-deoxy-5'-o-(dimethoxytrityl)-5,6-dihydrouridine
  • 2’-Azido-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine
  • 5-Me-3’-dU-2’-phosphoramidite