N-((R)-1-Benzylpyrrolidin-3-yl)acetamide

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Names

[ CAS No. ]:
114636-33-8

[ Name ]:
N-((R)-1-Benzylpyrrolidin-3-yl)acetamide

[Synonym ]:
(R)-(+)-1-Benzyl-3-acetylaminopyrrolidine

Chemical & Physical Properties

[ Density]:
1.139 g/mL at 25ºC(lit.)

[ Boiling Point ]:
307-308ºC760 mm Hg(lit.)

[ Molecular Formula ]:
C13H18N2O

[ Molecular Weight ]:
218.29500

[ Flash Point ]:
110ºC

[ Exact Mass ]:
218.14200

[ PSA ]:
32.34000

[ LogP ]:
1.72580

[ Vapour Pressure ]:
3.33E-06mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.5470(lit.)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • Ethanoic anhydride
  • (3R)-1-Benzylpyrrolidin-3-amin
  • (3S)-1-Benzyl-3-methylpyrrolidine
  • (r)-1-benzyl-3-mesyloxy pyrrolidine
  • (3S)-3-azido-1-(phenylmethyl)pyrrolidine

DownStream

  • 1-Benzyl-N-ethyl-3-pyrrolidinamine

Related Compounds

  • N-(1-benzylpyrrolidin-3-yl)-2-chloroacetamide
  • N-(1-Benzyl-3-pyrrolidinyl)acetamide
  • N-(1-benzylpyrrolidin-3-yl)-N-(2-methoxyphenyl)propanamide
  • N-(1-benzylpyrrolidin-3-yl)-N-phenylpropanamide
  • N-[(1-benzylpyrrolidin-3-yl)methyl]-2,2,2-trifluoroacetamide
  • N-(1-benzylpyrrolidin-3-yl)-3-nitropyridin-2-amine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 2-(2-Aminoethyl)-5-bromophenol
  • ethyl 4-(3-amino-4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate
  • tert-Butyl-DL-alanine