2'-O-(tert-Butyldimethylsilyl)taxol

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Names

[ CAS No. ]:
114655-02-6

[ Name ]:
2'-O-(tert-Butyldimethylsilyl)taxol

[Synonym ]:
2'-O-(2-METHOXYETHYL)-5-METHYL-URIDINE
2'-O-TBDMS paclitaxel
2'-(tert-butyldimethylsilyl)taxol
2'-tert-butyldimethylsilylpaclitaxel
2'-O-TBS-paclitaxel
2'-O-(t-butyldimethylsilyl)paclitaxel
2'-O-(tert-Butyldimethylsilyl) Paclitaxel

Chemical & Physical Properties

[ Molecular Formula ]:
C53H65NO14Si

[ Molecular Weight ]:
968.16700

[ Exact Mass ]:
967.41700

[ PSA ]:
210.29000

[ LogP ]:
7.15610

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Paclitaxel
  • tert-Butyldimethylsilyl chloride

DownStream

  • 2'-O-(tert-butyldimethylsilyl)-6,7-dehydropaclitaxel

Related Compounds

  • 2'-O-(tert-butyldimethylsilyl)-4-O-deacetyl-2-O-debenzoyl-7-O-(triethylsilyl)paclitaxel
  • 2'-O-(tert-butyldimethylsilyl)-6,7-dehydropaclitaxel
  • 2'-O-tert-butyldimethylsilyl-7-O-triethylsilyldocetaxel
  • 2'-O-(tert-Butyldimethylsilyl)-N2-(isobutyryl)guanosin-3'-(2-chlorphenyl)(2-cyanaethyl)phosphat
  • 2'-O-(tert-Butyldimethylsilyl)-6|A-hydroxy 7-epi-Paclitaxel
  • 2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine
  • Benzene,1-bromo-2-(1-methylethoxy)-4-nitro-
  • (3-methylbutyl)({[1-(propan-2-yl)-1H-pyrazol-3-yl]methyl})amine
  • 2-(azetidin-3-yloxy)-N-pentylpropanamide
  • (2-Cyclopropyl-1-methyl-1H-benzo[d]imidazol-5-yl)methanamine
  • [4-[4-(Trifluoromethyl)phenoxy]phenyl]hydrazine
  • (3S)-3-[(4-bromophenyl)amino]butanamide
  • tert-Butyl 7-nitro-1-oxo-3,4-dihydroisoquinoline-2(1H)-carboxylate
  • N-[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-5-yl]urea
  • (1R)-1-(2-methoxy-4-methylphenyl)ethan-1-ol
  • (2,2-Dimethylpropyl)[3-(morpholin-4-yl)propyl]amine
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