2'-O-(tert-Butyldimethylsilyl)taxol

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Names

[ CAS No. ]:
114655-02-6

[ Name ]:
2'-O-(tert-Butyldimethylsilyl)taxol

[Synonym ]:
2'-O-(2-METHOXYETHYL)-5-METHYL-URIDINE
2'-O-TBDMS paclitaxel
2'-(tert-butyldimethylsilyl)taxol
2'-tert-butyldimethylsilylpaclitaxel
2'-O-TBS-paclitaxel
2'-O-(t-butyldimethylsilyl)paclitaxel
2'-O-(tert-Butyldimethylsilyl) Paclitaxel

Chemical & Physical Properties

[ Molecular Formula ]:
C53H65NO14Si

[ Molecular Weight ]:
968.16700

[ Exact Mass ]:
967.41700

[ PSA ]:
210.29000

[ LogP ]:
7.15610

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Paclitaxel
  • tert-Butyldimethylsilyl chloride

DownStream

  • 2'-O-(tert-butyldimethylsilyl)-6,7-dehydropaclitaxel

Related Compounds

  • 2'-O-(tert-butyldimethylsilyl)-4-O-deacetyl-2-O-debenzoyl-7-O-(triethylsilyl)paclitaxel
  • 2'-O-(tert-butyldimethylsilyl)-6,7-dehydropaclitaxel
  • 2'-O-tert-butyldimethylsilyl-7-O-triethylsilyldocetaxel
  • 2'-O-(tert-Butyldimethylsilyl)-N2-(isobutyryl)guanosin-3'-(2-chlorphenyl)(2-cyanaethyl)phosphat
  • 2'-O-(tert-Butyldimethylsilyl)-6|A-hydroxy 7-epi-Paclitaxel
  • 2'-O-(tert-butyldimethylsilyl)-3',5'-O-(di-tert-butylsilanediyl)guanosine
  • isopropyl 4H-furo[3,2-b]pyrrole-5-carboxylate
  • 2-Carboxyethyl 2-cyano-2-propenoate
  • 1-(Benzyloxy)-3-(tert-butoxy)benzene
  • Ethyl (4aS,9bR)-5-(2-amino-2-oxoethyl)-6-bromo-1,3,4,4a,5,9b-hexahydro-2H-pyrido[4,3-b]indole-2-carboxylate
  • (1r,4r)-4-(Methylcarbamoyl)cyclohexane-1-carboxylic acid
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-aminoacetate
  • (R)-N-(3-Methyl-1-(pyrrolidin-1-yl)butan-2-yl)-P,P-diphenylphosphinic amide
  • tert-butyl N-[(2S)-3-oxo-4-(thiophen-2-yl)butan-2-yl]carbamate
  • 4-[1-(4-iodophenyl)-1,2-dimethylpropyl]Phenol
  • 2-(3-Chloropyridin-2-yl)-5-(trifluoromethyl)pyrazole-3-carbaldehyde
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