(2R,4R)-n-Boc-2-(Fluoromethyl)-4-hydroxypyrrolidine

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Names

[ CAS No. ]:
114676-97-0

[ Name ]:
(2R,4R)-n-Boc-2-(Fluoromethyl)-4-hydroxypyrrolidine

Chemical & Physical Properties

[ Density]:
1.151

[ Boiling Point ]:
302.7ºC at 760 mmHg

[ Melting Point ]:
98-99ºC

[ Molecular Formula ]:
C10H18FNO3

[ Molecular Weight ]:
219.25300

[ Exact Mass ]:
219.12700

[ PSA ]:
49.77000

[ LogP ]:
1.26410

[ Index of Refraction ]:
1.471

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R,4R)-1-(tert-butoxycarbonyl)-2-(fluoromethyl)-4-(tetrahydropyran-2-yloxy)pyrrolidine
  • Di-tert-butyl dicarbonate
  • N-Boc-cis-4-hydroxy-D-proline methyl ester
  • D-Proline, 4-hydroxy-, methyl ester hydrochloride
  • N-α-tert-butyloxycarbonyl-cis-4-(2-tetrahydropyranyloxy)-D-prolinol
  • (2R,4R)-tert-butyl 2-(((methylsulfonyl)oxy)methyl)-4-((tetrahydro-2H-pyran-2-yl)oxy)pyrrolidine-1-carboxylate
  • cis-4-Hydroxyproline

DownStream

Related Compounds

  • N-Hydroxy-2-(hydroxymethyl)-1H-indole-5-carboximidamide
  • tert-Butyl 2-(((5-nitropyridin-2-yl)amino)methyl)piperidine-1-carboxylate
  • N1-(3-fluoro-4-methylphenyl)-N2-((3-methoxytetrahydrothiophen-3-yl)methyl)oxalamide
  • N1-(2-chlorophenyl)-N2-((3-methoxytetrahydrothiophen-3-yl)methyl)oxalamide
  • 4-(4-chlorophenyl)-4-oxo-N-(1-(tetrahydrofuran-3-yl)-1H-pyrazol-4-yl)butanamide
  • tert-Butyl 2-(((5-nitro-1H-benzo[d]imidazol-2-yl)amino)methyl)piperidine-1-carboxylate
  • tert-Butyl 2-(((5-nitrobenzo[d]oxazol-2-yl)amino)methyl)piperidine-1-carboxylate
  • tert-Butyl 2-(((3-chloroquinoxalin-2-yl)amino)methyl)piperidine-1-carboxylate
  • tert-Butyl 2-(((1-(4-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)amino)methyl)piperidine-1-carboxylate
  • tert-Butyl 2-(((1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)amino)methyl)piperidine-1-carboxylate
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