4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

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Names

[ CAS No. ]:
114772-55-3

[ Name ]:
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

[Synonym ]:
4'-{[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}-2-biphenylcarbonitrile
x8011
i06-2569
4'-{[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile
[1,1'-Biphenyl]-2-carbonitrile, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]-
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
605.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H22ClN3O

[ Molecular Weight ]:
379.883

[ Flash Point ]:
320.1±31.5 °C

[ Exact Mass ]:
379.145142

[ PSA ]:
61.84000

[ LogP ]:
3.70

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.609

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Butyl-4-chloro-5-formylimidazole
  • 4-Bromomethyl-2-cyanobiphenyl
  • 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde
  • (2-Butyl-5-chloro-1H-imidazol-4-yl)methanol
  • 4'-Methyl-2-cyanobiphenyl
  • 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline
  • N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE
  • 4,4-dimethyl-2-[2-(4-methylphenyl)phenyl]-5H-1,3-oxazole
  • 2-Methoxybenzoic acid
  • o-anisoyl chloride

DownStream

  • Losartan potassium
  • Trityl losartan
  • Losartan

Related Compounds

  • (E)-3-(3,4-dimethoxyphenyl)-N-(4-((6-methylpyridazin-3-yl)amino)phenyl)acrylamide
  • N-(4-((6-methylpyridazin-3-yl)amino)phenyl)-2-oxo-2H-chromene-3-carboxamide
  • 4-(N,N-dimethylsulfamoyl)-N-(4-((6-methylpyridazin-3-yl)amino)phenyl)benzamide
  • N-(2-((6-methylpyridazin-3-yl)amino)ethyl)-4-(trifluoromethoxy)benzenesulfonamide
  • 3,5-dimethyl-N-(2-((6-methylpyridazin-3-yl)amino)ethyl)isoxazole-4-sulfonamide
  • 2,5-difluoro-N-(2-((6-methylpyridazin-3-yl)amino)ethyl)benzenesulfonamide
  • 5-methoxy-2,4-dimethyl-N-(2-((6-methylpyridazin-3-yl)amino)ethyl)benzenesulfonamide
  • N-(2-((6-methylpyridazin-3-yl)amino)ethyl)ethanesulfonamide
  • N-(4-((6-methylpyridazin-3-yl)amino)phenyl)pyridine-3-sulfonamide
  • 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-((6-methylpyridazin-3-yl)amino)ethyl)urea
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