4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

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Names

[ CAS No. ]:
114772-55-3

[ Name ]:
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

[Synonym ]:
4'-{[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}-2-biphenylcarbonitrile
x8011
i06-2569
4'-{[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile
[1,1'-Biphenyl]-2-carbonitrile, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]-
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
605.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H22ClN3O

[ Molecular Weight ]:
379.883

[ Flash Point ]:
320.1±31.5 °C

[ Exact Mass ]:
379.145142

[ PSA ]:
61.84000

[ LogP ]:
3.70

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.609

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Butyl-4-chloro-5-formylimidazole
  • 4-Bromomethyl-2-cyanobiphenyl
  • 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde
  • (2-Butyl-5-chloro-1H-imidazol-4-yl)methanol
  • 4'-Methyl-2-cyanobiphenyl
  • 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline
  • N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE
  • 4,4-dimethyl-2-[2-(4-methylphenyl)phenyl]-5H-1,3-oxazole
  • 2-Methoxybenzoic acid
  • o-anisoyl chloride

DownStream

  • Losartan potassium
  • Trityl losartan
  • Losartan

Related Compounds

  • 1-(2,2-Difluoropropoxy)-2-iodocycloheptane
  • 1-(Bromomethyl)-1-(2,2-difluoropropoxy)-4-methylcyclohexane
  • 1-(Bromomethyl)-1-(2,2-difluoropropoxy)-3-methylcyclohexane
  • 1-(2,2-Difluoropropoxy)-1-(iodomethyl)-3-methylcyclohexane
  • 1-[2-Bromo-1-(2,2-difluoropropoxy)ethyl]-3-methylbenzene
  • 12-Ethyl-4,8-dioxa-1,12,15-triazadispiro[5.2.5^{9}.2^{6}]hexadecane
  • 2-[4-(2,5-Difluorophenyl)phenyl]oxetane
  • 1-[2-Bromo-1-(pentan-3-yloxy)ethyl]-4-chlorobenzene
  • 1-Bromo-2-[2-bromo-1-(pentan-3-yloxy)ethyl]benzene
  • 4,8,12-Trioxa-1,15-diazadispiro[5.2.5^{9}.2^{6}]hexadecane
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