4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

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Names

[ CAS No. ]:
114772-55-3

[ Name ]:
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

[Synonym ]:
4'-{[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}-2-biphenylcarbonitrile
x8011
i06-2569
4'-{[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile
[1,1'-Biphenyl]-2-carbonitrile, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]-
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
605.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H22ClN3O

[ Molecular Weight ]:
379.883

[ Flash Point ]:
320.1±31.5 °C

[ Exact Mass ]:
379.145142

[ PSA ]:
61.84000

[ LogP ]:
3.70

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.609

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Butyl-4-chloro-5-formylimidazole
  • 4-Bromomethyl-2-cyanobiphenyl
  • 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde
  • (2-Butyl-5-chloro-1H-imidazol-4-yl)methanol
  • 4'-Methyl-2-cyanobiphenyl
  • 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline
  • N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE
  • 4,4-dimethyl-2-[2-(4-methylphenyl)phenyl]-5H-1,3-oxazole
  • 2-Methoxybenzoic acid
  • o-anisoyl chloride

DownStream

  • Losartan potassium
  • Trityl losartan
  • Losartan

Related Compounds

  • 1-Phenyl-3-((2-(pyrrolidin-1-yl)pyrimidin-4-yl)methyl)urea
  • N-(2-chloro-4-methylphenyl)-2-((3-(2-hydroxyethyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
  • N-(2-hydroxy-2-methyl-3-(methylthio)propyl)-4-methoxy-3-methylbenzenesulfonamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 4-Chloro-5-cyclopropoxy-N,N-dimethylpicolinamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide