Diludine

Suppliers

Names

[ CAS No. ]:
1149-23-1

[ Name ]:
Diludine

[Synonym ]:
Diethyl 1,4-dihydro-2,6-dimethyl-3-5-pyridinedicarboxylate
Diludine
Hantzsch ester
diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate
1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, diethyl ester
Hantzsch's dihydropyridine
EINECS 214-561-6
Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
3,5-Diethoxycarbonyl-1,4-dihydro-2,6-dimethylpyridine
Diethyl 2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
Diethyl 1,4-dihydro-3,5-pyridinecarboxylate
MFCD00005951
diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
351.8±42.0 °C at 760 mmHg

[ Melting Point ]:
178-183 °C(lit.)

[ Molecular Formula ]:
C13H19NO4

[ Molecular Weight ]:
253.294

[ Flash Point ]:
166.6±27.9 °C

[ Exact Mass ]:
253.131409

[ PSA ]:
64.63000

[ LogP ]:
2.52

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.489

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7970100
CHEMICAL NAME :
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, diethyl ester
CAS REGISTRY NUMBER :
1149-23-1
LAST UPDATED :
199806
DATA ITEMS CITED :
4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4769382
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>32 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
URXXAF U.S.S.R. Patent Document. (Gosudarstvennyi Komitet SSSR po Delam Izobretenii i Otkrytii, Malyi Tcherkasski pereulok 2/6, Moscow, Russia). Volume(issue)/page/year: #0546335
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>30 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4769382
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>12 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4769382

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
US7970100

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Formaldehyde
  • Ethyl acetoacetate
  • Ammonium acetate
  • Propanedioic acid,1-ethyl 3-methyl ester
  • 2H-1,3-Oxazine,tetrahydro-
  • Ethyl (2Z)-3-amino-2-butenoate
  • 3,5-Diethoxycarbonyl-2,6-dimethylpyridine
  • 3-Phenyloxazolidine
  • Aminoform
  • Ethanol

DownStream

  • 3,5-Diethoxycarbonyl-2,6-dimethylpyridine
  • 2-(4-METHOXYBENZYL)MALONONITRILE
  • diethyl 1,2,6-trimethyl-4H-pyridine-3,5-dicarboxylate
  • 2,4,6-tris(2,2-diphenylhydrazinyl)benzene-1,3,5-tricarbonitrile
  • Diethyl fumarate
  • diethylmaleate
  • Diethyl succinate
  • 2-[(4-chlorophenyl)methyl]propanedinitrile
  • N-(4-methoxyphenyl)-4-phenyl-2-butylamine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Supported core@shell electrocatalysts for fuel cells: close encounter with reality.

Sci. Rep. 3 , 1309, (2013)

Core@shell electrocatalysts for fuel cells have the advantages of a high utilization of Pt and the modification of its electronic structures toward enhancement of the activities. In this study, we sug...

[Medico-biological aspects of biochemistry of amines and other nitrogen bases].

Vestn. Ross. Akad. Med. Nauk (2) , 12-7, (1995)

The art-of-the-state and possible perspectives for studies of the properties of amine oxidases which are medically significant are briefly outlined. Due to the studies conducted at the Research Instit...

[Possibility of preventing muscular dystrophy in E avitaminosis with alpha-tocopheronolactone and diludin].

Vopr. Pitan. (2) , 44-9, (1982)

The efficacy of pharmacopeial alpha-tocopheryl acetate, alpha-tocopheronolactone and the antioxidant diludin was studied as to the possibilities of preventing E-hypovitaminosis muscle dystrophy in rab...


More Articles