(2S-cis)-5,6-dihydro-N,N-dimethyl-2-[2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]ethyl]-2H-pyran-5-acetamide

Names

[ CAS No. ]:
115140-92-6

[ Name ]:
(2S-cis)-5,6-dihydro-N,N-dimethyl-2-[2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]ethyl]-2H-pyran-5-acetamide

[Synonym ]:
(2S-cis)-5,6-dihydro-N,N-dimethyl-2-(2-{[(1,1-dimethylethyl)diphenylsilyl]oxy}ethyl)-2H-pyran-5-acetamide

Chemical & Physical Properties

[ Molecular Formula ]:
C27H37NO3Si

[ Molecular Weight ]:
451.67300

[ Exact Mass ]:
451.25400

[ PSA ]:
38.77000

[ LogP ]:
4.00260

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (3aS,7R,7aR)-7-iodohexahydro-2H-furo[3,2-b]pyran-2-one
  • (R,E)-N-(1-phenylethyl)hexa-3,5-dienamide
  • [S-(R*,R*)]-5,6-dihydro-N-(1-phenylethyl)-2H-pyran-2-acetamide

DownStream

  • Pseudomonic Acid C
  • 2-((3S,4R,5R,6S)-6-(2-((tert-butyldiphenylsilyl)oxy)ethyl)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)-N,N-dimethylacetamide
  • (2R,3R,E)-2-((tert-butyldimethylsilyl)oxy)-6-((3aS,4S,7S,7aR)-4-(2-((tert-butyldiphenylsilyl)oxy)ethyl)-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-7-yl)-3-methylhex-4-en-1-ol
  • tert-butyl(2-((3aS,4S,7S,7aR)-7-((4R,5R,E)-5-((tert-butyldimethylsilyl)oxy)-6-iodo-4-methylhex-2-en-1-yl)-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-4-yl)ethoxy)diphenylsilane
  • 2-((3aS,4S,7S,7aR)-7-((4R,5S,E)-5-((tert-butyldimethylsilyl)oxy)-4-methylhex-2-en-1-yl)-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-4-yl)ethanol