EIPA

Suppliers

Names

[ CAS No. ]:
1154-25-2

[ Name ]:
EIPA

[Synonym ]:
ethylisopropylamiloride
MFCD00151710
3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide
3-amino-6-chloro-n-(diaminomethylene)-5-[ethyl(isopropyl)amino]pyrazine-2-carboxamide
2-Pyrazinecarboxamide, 3-amino-6-chloro-N-(diaminomethylene)-5-[ethyl(1-methylethyl)amino]-
3-Amino-6-chloro-N-(diaminomethylene)-5-[ethyl(isopropyl)amino]-2-pyrazinecarboxamide
EIPA

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
543.9±60.0 °C at 760 mmHg

[ Melting Point ]:
202-205ºC(lit.)

[ Molecular Formula ]:
C11H18ClN7O

[ Molecular Weight ]:
299.760

[ Flash Point ]:
282.8±32.9 °C

[ Exact Mass ]:
299.126129

[ PSA ]:
134.01000

[ LogP ]:
4.86

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.665

[ Storage condition ]:
2-8℃

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
UN 2811

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells.

Nat. Commun. 6 , 6240, (2015)

Epstein-Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal epithelial cells remain elusiv...

Local pH domains regulate NHE3-mediated Na⁺ reabsorption in the renal proximal tubule.

Am. J. Physiol. Renal Physiol. 307(11) , F1249-62, (2014)

The proximal tubule Na(+)/H(+) exchanger 3 (NHE3), located in the apical dense microvilli (brush border), plays a major role in the reabsorption of NaCl and water in the renal proximal tubule. In resp...

Production of new amilorides as potent inhibitors of mitochondrial respiratory complex I.

Biosci. Biotechnol. Biochem. 79 , 1061-6, (2015)

Amilorides, well-known inhibitors of Na(+)/H(+) antiporters, have also shown to inhibit bacterial and mitochondrial NADH-quinone oxidoreductase (complex I). Since the membrane subunits ND2, ND4, and N...


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Related Compounds

  • EIPA hydrochloride
  • (1S,4S)-7-Fluoro-2-oxa-5-azabicyclo[2.2.1]heptane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 6-Amino-4-(difluoromethyl)-5-iodopicolinonitrile
  • 6-Amino-5-(difluoromethyl)-4-fluoropyridine-3-sulfonamide
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 6-(azetidin-1-yl)-N-methylpyrimidin-4-amine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide