7-O-(Triethylsilyl)-10-deacetyl Baccatin III

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Names

[ CAS No. ]:
115437-18-8

[ Name ]:
7-O-(Triethylsilyl)-10-deacetyl Baccatin III

[Synonym ]:
7-O-triethylsilyl-10-DAB
10-Deacetyl-7-triethylsilylbaccatin III
7-O-triethylsilyl-10-deacetyl baccatin III
7-O-Triethylsilyl-10-desacetylbaccatin III
7-triethysilyl-10-deacetylbaccatin III

Chemical & Physical Properties

[ Molecular Formula ]:
C35H50O10Si

[ Molecular Weight ]:
658.85100

[ Exact Mass ]:
658.31700

[ PSA ]:
148.82000

[ LogP ]:
4.11130

[ Index of Refraction ]:
1.572

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 10-Deacetylbaccatin III
  • Chlorotriethylsilane
  • 7-TES-9,10-diketobaccatin III
  • tert-Butyldimethylsilyl chloride
  • 13-Acetyl-7-(triethylsilyl)baccatin III

DownStream

  • 10-Deacetylbaccatin III
  • 13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III
  • 7,10-dimethoxy-Baccatin III
  • Paclitaxel
  • Baccatin III
  • Docetaxal
  • 3'-N-debenzoyltaxol
  • 7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III
  • cabazitaxel
  • 7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Baccatin III

Related Compounds

  • 7,13-Bis-O-(triethylsilyl)-10-deacetyl Baccatin III
  • 7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III
  • 13-O-trimethylsilyl-7,10-bis-O-triethylsilyl-10-deacetyl baccatin III
  • 7,13-Bis-O-(triethylsilyl)-10-deacetyl-10-oxo Baccatin III
  • 7-O-(Triethylsilyl) Baccatin III
  • 2-Debenzoyl-7,10-bis[O-(triethylsilyl)]-10-deacetyl-13-O-trimethylsilyl Baccatin III