bistratene A

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Names

[ CAS No. ]:
115566-02-4

[ Name ]:
bistratene A

[Synonym ]:
bistramide A
L-threo-hydroxyleucine

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₀H₆₈N₂O₈

[ Molecular Weight ]:
704.97700

[ Exact Mass ]:
704.49800

[ PSA ]:
150.40000

[ LogP ]:
7.60960

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EB8000000

CHEMICAL NAME :: Bistramide A

CAS REGISTRY NUMBER :: 115566-02-4

LAST UPDATED :: 199707

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C40-H68-N2-O8

MOLECULAR WEIGHT :: 705.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,1129,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 ug/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,1129,1988

Safety Information

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R23/24/25

[ Safety Phrases ]:
S22

[ RIDADR ]:
UN 3462 6.1/PG 2

Related Compounds

actinoplanone A
Thapsuine A
Apocynol A
(2S)-N-[(2S,5S,8S,11R,12S,15S,18S,21R)-5-[(3-bromo-4-methoxyphenyl)methyl]-2-[(2S)-butan-2-yl]-15-[3-(carbamoylamino)propyl]-21-hydroxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]-2-(butanoyla
Pseudoanguillosporin A
Digitoside A
4-[2-(Chloromethyl)-3-methylbutyl]-1,2,3-thiadiazole
4-[2-(bromomethyl)butyl]-2-methyl-2H-1,2,3-triazole
2-{[1-(Chloromethyl)-2-methylcyclopropyl]methyl}-1,3-thiazole
1-(Chloromethyl)-2-methyl-1-(pent-4-en-1-yl)cyclopropane
N-[(3-bromocyclobutyl)methyl]-1-methylpiperidine-4-carboxamide
5-[5-(Chloromethyl)pyridin-3-yl]-2-fluoropyridine
3-(2-Bromo-6-fluorophenyl)-5-(chloromethyl)pyridine
({3-[5-(Chloromethyl)pyridin-3-yl]phenyl}methyl)dimethylamine
3-(Chloromethyl)-5-(2,5-dichlorophenyl)pyridine
3-(Chloromethyl)-5-(2-chlorophenyl)pyridine

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