acetol

Names

[ CAS No. ]:
116-09-6

[ Name ]:
acetol

[Synonym ]:
Hydroxyacetone
1-Hydroxyacetone
EINECS 204-124-8
Hydroxy-2-propanone
2-Propanone, 1-hydroxy-
MFCD00004669
1-Hydroxypropan-2-One

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
145.5±0.0 °C at 760 mmHg

[ Melting Point ]:
−17 °C(lit.)

[ Molecular Formula ]:
C₃H₆O₂

[ Molecular Weight ]:
74.078

[ Flash Point ]:
52.2±11.0 °C

[ Exact Mass ]:
74.036781

[ PSA ]:
37.30000

[ LogP ]:
-0.78

[ Vapour Pressure ]:
1.9±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.397

[ Stability ]:
Stable. Flammable. Incompatible with strong oxidizing agents, strong acids. Protect from moisture - hygroscopic.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC2800000

CHEMICAL NAME :: 2-Propanone, 1-hydroxy-

CAS REGISTRY NUMBER :: 116-09-6

BEILSTEIN REFERENCE NO. :: 0605368

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C3-H6-O2

MOLECULAR WEIGHT :: 74.09

WISWESSER LINE NOTATION :: Q1V1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 500 ug/plate

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 47,2461,1983

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
F+

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
UN 1224 3/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
UC2800000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29144090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Glycerol
D-(+)-Glucose
Propylene Glycol
Methylglyoxal
Sorbitol
D-(+)-Xylose
Cellulose microcrystalline
Propargyl alcohol
1-Acetoxyacetone
3-Phenyl-2-propyn-1-ol

DownStream

2-(hydroxymethyl)-1-methylquinolin-4-one
2-Ethylbenzofuran
2,3-dimethylbenzofuran
2-Methylbenzofuran
4-Methyl-1,3-oxazol-2-amine
(S)-(+)-1,2-Propanediol
(R)-(-)-1,2-Propanediol
hexanedione
1-HYDROXY-2-BUTANONE
4-Methyl-2(5H)-furanone

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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