(5E)-BiMatoprost

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Names

[ CAS No. ]:
1163135-95-2

[ Name ]:
(5E)-BiMatoprost

[Synonym ]:
4-Androstene-3,17-dione-19-ol
15R-bimatoprost
19-hydroxyandrostenedione
4-androsten-19-ol-3,17-dione
(5E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-N-ethyl-5-heptenamide
(5E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
19-Hydroxyandrostendione
5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5E)-
19-Hydroxy-androst-4-en-3,17-dion
15-epi-bimatoprost
19-Hydroxy-4-androstene-3,17-dione
5-trans bimatoprost

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
629.8±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H37NO4

[ Molecular Weight ]:
415.57

[ Flash Point ]:
334.7±31.5 °C

[ Exact Mass ]:
415.272247

[ PSA ]:
89.79000

[ LogP ]:
1.98

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.591

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl ester of 5-trans-binaprost acid
  • Ethylamine
  • CHEMPACIFIC 59929

DownStream

Related Compounds

  • (5E)-5-[(2,4-dichlorophenyl)methylidene]-3-(1-phenylethyl)-2-sulfanylidene-1,3-thiazolidin-4-one
  • (5E)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-3-(4-nitrophenyl)-2-sulfanylidene-1,3-thiazolidin-4-one
  • (5E,6E)-5,6-bis(2-(3-methoxyphenyl)hydrazono)hexahydro-1H-isoindole-1,3(2H)-dione
  • (5E)-5-[(1-ethyl-1H-indol-3-yl)methylidene]-3-(2-fluorobenzyl)imidazolidine-2,4-dione
  • (5E)-5-[(3-hydroxyphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one
  • (5E)-2-methylhepta-2,5-dien-4-ol
  • 3-((1-(5-Methylisoxazole-4-carbonyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(2-(Thiophen-3-yl)acetyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(4-Methylthiazole-5-carbonyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(6-Ethoxynicotinoyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(Benzo[b]thiophene-2-carbonyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(Tetrahydrofuran-3-carbonyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(3-(3-Chlorophenyl)propanoyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(6-Methoxynicotinoyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(2,3-Dihydrobenzo[b][1,4]dioxine-5-carbonyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
  • 3-((1-(2-(Benzyloxy)acetyl)piperidin-3-yl)oxy)pyrazine-2-carbonitrile
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