Aflatoxin G1
Suppliers
Names
[ CAS No. ]:
1165-39-5
[ Name ]:
Aflatoxin G1
[Synonym ]:
AF G1
MFCD00005089
Aflatoxin G(1)
1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR,10aS)-
aflatoxin g1 solution
AFLATOXIN G
EINECS 214-615-9
Aflatoxin G1,crystalline
(7ar-cis)-10a-tetrahydro-5-methoxy
10a-tetrahydro-5-methoxy
Aflatoxin G1
(7aR,10aS)-5-Methoxy-3,4,7a,10a-tetrahydro-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
612.1±55.0 °C at 760 mmHg
[ Melting Point ]:
244-246ºC
[ Molecular Formula ]:
C17H12O7
[ Molecular Weight ]:
328.273
[ Flash Point ]:
274.1±31.5 °C
[ Exact Mass ]:
328.058289
[ PSA ]:
84.20000
[ LogP ]:
-0.17
[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C
[ Index of Refraction ]:
1.680
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LV1720000
- CAS REGISTRY NUMBER :
- 1165-39-5
- BEILSTEIN REFERENCE NO. :
- 1299768
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 39
- MOLECULAR FORMULA :
- C17-H12-O7
- MOLECULAR WEIGHT :
- 328.29
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14900 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - pleural effusion Liver - jaundice, other or unclassified Endocrine - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 785 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4100 ug/kg/22W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 mg/kg/30W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 24 mg/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8 mg/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5600 ug/kg/2W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- Sperm Morphology
- TYPE OF TEST :
- DNA adduct
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Primate - monkey Kidney
- DOSE/DURATION :
- 2 mg/L
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 48,1647,1972 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 10,51,1976 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 56,245,1993 TOXICOLOGY REVIEW LLOYA2 Lloydia. (Cincinnati, OH) V.1-41, 1938-78. For publisher information, see JNPRDF. Volume(issue)/page/year: 38,21,1975 TOXICOLOGY REVIEW BAREA8 Bacteriological Reviews. (Washington, DC) V.1-41, 1937-77. Volume(issue)/page/year: 30,460,1966 TOXICOLOGY REVIEW PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 10,85,1974 TOXICOLOGY REVIEW IJNDAN Indian Journal of Nutrition and Dietetics. (Sri Avinashilingam Home Science College for Women, Coimbatore 641 043, India) V.7- 1970- Volume(issue)/page/year: 8,85,1971
Safety Information
[ Symbol ]:
GHS02, GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H304-H315-H319-H340-H350-H372
[ Precautionary Statements ]:
P201-P210-P301 + P310-P305 + P351 + P338-P308 + P313-P331
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T: Toxic;T+: Very toxic;F: Flammable;Xn: Harmful;
[ Risk Phrases ]:
R45
[ Safety Phrases ]:
53-28-36/37-45-62-26-16-7-36
[ RIDADR ]:
UN 3462 6
[ WGK Germany ]:
3
[ RTECS ]:
LV1720000
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1(a)
Synthetic Route
Articles
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