(R)-Duloxetine

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Names

[ Name ]:
(R)-Duloxetine

[Synonym ]:
Cymbalta
Ariclaim
R-Duloxetine HCl
(3R)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine hydrochloride (1:1)
2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γR)-, hydrochloride (1:1)
UNII-TK9VOT90JQ
N-methyl-3-napthalen-1-oxy-3-thiophen-2-yl-1-amine

Chemical & Physical Properties

[ Density]:
1.158

[ Boiling Point ]:
466.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₀ClNOS

[ Molecular Weight ]:
333.875

[ Flash Point ]:
235.7ºC

[ Exact Mass ]:
333.095398

[ PSA ]:
49.50000

[ LogP ]:
5.82380

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Related Compounds

(R)-Duloxetine Hydrochloride
(R)-(+)-S-methyl tert-butylphenylphosphinothiolate
((R)-6-benzylamino-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-carbamic acid tert-butyl ester
(R-(R*,R*))-N-(2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-2-o xoacetamide
(R)-1-(4-METHOXYPHENYL)ETHANOL
(R)-tert-butyl 6-hydroxy-1,4-oxazepane-4-carboxylate
5-(3,4-difluorophenyl)-1-methyl-1H-1,2,3-triazole
5-[4-(Benzyloxy)-2,6-difluorophenyl]-2-methoxypyrimidine
4-(4-Amino-2,6-dichlorophenyl)benzamide
4-(4-Ethoxypyridin-2-yl)benzamide
4-(7-methyl-2,3-dihydro-1H-indol-4-yl)benzamide
4-(4-Carbamoylphenyl)-2-methyl-1,3-oxazole-5-carboxylic acid
4-[3-Amino-4-(dimethylamino)pyridin-2-yl]benzamide
4-(3,5-diethyl-1-methyl-1H-pyrazol-4-yl)benzamide
(3S)-3-amino-3-[5-(methylsulfanyl)-1,3-thiazol-2-yl]propanamide
3-{[(Tert-butoxy)carbonyl]amino}-3-(1,2-thiazol-4-yl)propanoic acid

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