(R)-Duloxetine

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Names

[ Name ]:
(R)-Duloxetine

[Synonym ]:
Cymbalta
Ariclaim
R-Duloxetine HCl
(3R)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine hydrochloride (1:1)
2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γR)-, hydrochloride (1:1)
UNII-TK9VOT90JQ
N-methyl-3-napthalen-1-oxy-3-thiophen-2-yl-1-amine

Chemical & Physical Properties

[ Density]:
1.158

[ Boiling Point ]:
466.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₀ClNOS

[ Molecular Weight ]:
333.875

[ Flash Point ]:
235.7ºC

[ Exact Mass ]:
333.095398

[ PSA ]:
49.50000

[ LogP ]:
5.82380

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Related Compounds

(R)-Duloxetine Hydrochloride
(R)-(+)-S-methyl tert-butylphenylphosphinothiolate
((R)-6-benzylamino-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-carbamic acid tert-butyl ester
(R-(R*,R*))-N-(2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-2-o xoacetamide
(R)-1-(4-METHOXYPHENYL)ETHANOL
(R)-tert-butyl 6-hydroxy-1,4-oxazepane-4-carboxylate
tert-butyl N-{2-oxo-1-[2-(propan-2-yloxy)phenyl]ethyl}carbamate
tert-butyl N-[1-(1-methyl-1H-pyrazol-5-yl)-2-oxoethyl]carbamate
tert-butyl N-[1-(3-bromopyridin-4-yl)-2-oxoethyl]-N-methylcarbamate
tert-butyl N-(1-{3-[(difluoromethyl)sulfanyl]phenyl}-2-oxoethyl)carbamate
tert-butyl N-methyl-N-{1-[1-methyl-3-(oxan-4-yl)-1H-pyrazol-4-yl]-2-oxoethyl}carbamate
1-(5-Bromo-2-chloropyridin-3-yl)cyclopropane-1-carbaldehyde
tert-butyl N-[1-(3-methyl-4-nitrophenyl)-2-oxoethyl]carbamate
tert-butyl N-[2-(2-methanesulfonylphenyl)-1-oxopropan-2-yl]-N-methylcarbamate
1-(3-Bromo-4,5-dimethoxyphenyl)cyclopropane-1-carbaldehyde
tert-butyl N-[1-(3-bromo-4-methylphenyl)-2-oxoethyl]-N-methylcarbamate

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