8-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one

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Names

[ CAS No. ]:
116815-03-3

[ Name ]:
8-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one

[Synonym ]:
8-chloro-1,2,3,4-tetrahydro-1-benzazepin-5-one

Chemical & Physical Properties

[ Density]:
1.234g/cm3

[ Boiling Point ]:
352.6ºC at 760mmHg

[ Molecular Formula ]:
C10H10ClNO

[ Molecular Weight ]:
195.64500

[ Flash Point ]:
167.1ºC

[ Exact Mass ]:
195.04500

[ PSA ]:
29.10000

[ LogP ]:
2.86640

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.562

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-[tert-butoxycarbonyl-(3-methoxycarbonyl-propyl)-amino]-4-chloro-benzoic acid methyl ester
  • 8-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
  • Methyl 2-amino-4-chlorobenzoate
  • N-p-toluenesulfonyl-4-chloro-anthranilic acid methyl ester
  • Methyl 4-chloro-2-{(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl ]amino}benzoate
  • 4-Chloro-2-nitrobenzoic acid
  • Benzoic acid,4-chloro-2-nitro-, methyl ester

DownStream

  • 2-Methyl-2-propanyl 8-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzaz epine-1-carboxylate

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 8-METHOXY-3,4-DIHYDRO-1H-BENZO[B]AZEPIN-5(2H)-ONE
  • 1-benzyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
  • 7-(TRIFLUOROMETHYL)-3,4-DIHYDRO-1H-BENZO[B]AZEPIN-5(2H)-ONE
  • 7-BROMO-3,4-DIHYDRO-1H-BENZO[B]AZEPIN-5(2H)-ONE
  • 7-METHYL-8-(TRIFLUOROMETHYL)-3,4-DIHYDRO-1H-BENZO[B]AZEPIN-5(2H)-ONE
  • 7,9-Dimethyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one hydrochloride
  • (2R)-2-{[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopropyl]formamido}-4-hydroxybutanoic acid
  • 3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-dimethylpropanoyl]-2-methyl-1,3-thiazolidine-4-carboxylic acid
  • (2R)-2-{2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-hydroxybutanoic acid
  • 4-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-fluorobenzoic acid
  • 2-{1-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopropanecarbonyl]-3-oxopiperazin-2-yl}acetic acid
  • 2-{3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]propanamido}-3-hydroxy-2-methylpropanoic acid
  • 2-[(Tert-butoxy)carbonyl]-8-(propan-2-yl)-2-azaspiro[4.5]decane-4-carboxylic acid
  • 2-[(Tert-butoxy)carbonyl]-8-(2-methylpropyl)-2,8-diazaspiro[4.5]decane-4-carboxylic acid
  • (2S)-2-[3-cyclobutyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-4-methylpentanoic acid
  • 1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-dimethylbutanoyl]-2-methylpiperidine-2-carboxylic acid
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