N-(2-Aminoethyl)isoquinoline-5-sulfonamide hydrochloride

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Names

[ CAS No. ]:
116970-50-4

[ Name ]:
N-(2-Aminoethyl)isoquinoline-5-sulfonamide hydrochloride

[Synonym ]:
H-9,DiHCl

Chemical & Physical Properties

[ Boiling Point ]:
479.8ºC at 760mmHg

[ Melting Point ]:
250-255ºC (dec)

[ Molecular Formula ]:
C11H13N3O2S

[ Molecular Weight ]:
251.30500

[ Flash Point ]:
243.9ºC

[ Exact Mass ]:
251.07300

[ PSA ]:
93.46000

[ LogP ]:
2.64380

[ Vapour Pressure ]:
2.3E-09mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX4897000
CHEMICAL NAME :
5-Isoquinolinesulfonamide, N-(2-aminoethyl)-, monohydrochloride
CAS REGISTRY NUMBER :
116970-50-4
LAST UPDATED :
199312
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H13-N3-O2-S.Cl-H
MOLECULAR WEIGHT :
287.79

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #92-264030
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #92-264030

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,2-Ethanediamine
  • Isoquinoline-5-sulfonyl chloride hydrochloride
  • 5-Isoquinolinesulfonic acid

DownStream

Related Compounds

  • (R)-(2'-methoxy-[1,1'-binaphthalen]-2-yl)diphenylphosphine oxide
  • 4-(Ethoxymethyl)-n-[2-(hydroxymethyl)-1,3-benzothiazol-5-yl]benzamide
  • 4-Hydroxy-2-(trifluoromethoxy)benzoic acid
  • Dibenzyl 2,4-dibromoglutarate
  • Ethyl 4-((5-(3-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-3-yl)methyl)piperazine-1-carboxylate
  • 7-Chloro-2-ethyl-1H-indole
  • N,N-dimethylbutanimidamide
  • Morpholine, 4-(acetyl-d3)-
  • [(2S,3R,4S,5S,6R)-6-(acetyloxymethyl)-4,5-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl] (E,5R,6S)-5-hydroxy-6-[(1S,3R,8S,9S,10R,13S,14S,17R)-1-hydroxy-10,13-dimethyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2,3-dimethylhept-2-enoate
  • 3,6,9,12,15,18-Hexazatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),3,5,8(13),9,11,15,17-nonaene-4,5,10,11,16,17-hexacarboxamide
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