Ethylenediamine-N,N'-bis((2-hydroxyphenyl)acetic acid)
Suppliers
Names
[ CAS No. ]:
1170-02-1
[ Name ]:
Ethylenediamine-N,N'-bis((2-hydroxyphenyl)acetic acid)
[Synonym ]:
N,N'-ethylenebis[2-(2-hydroxyphenyl)glycine]
CHEL-138
N,N'-ethylenebis[2-(o-hydroxyphenolic)glycine]
Ethylenebisiminobis(2-hydroxyphenylacetic acid)
ETHYLENEDIAMINEDI(ORTHO-HYDROXYPHENYLACETICACID)
ETHYLENEDIAMINEDI(2-HYDROXYPHENYLACETICACID)
EDDHA
ethylenediamine-bis(o-hydroxyphenyl)acetic acid
EDHPA
EthylenediaMine-N,N
ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid)
ethylenediamine di-o-hydroxyphenylacetic acid
EINECS 214-625-3
ETHYLENEBIS-ORTHO-HYDROXYPHENYLGLYCINE
Chemical & Physical Properties
[ Density]:
1.417 g/cm3
[ Boiling Point ]:
620.3ºC at 760 mmHg
[ Molecular Formula ]:
C18H20N2O6
[ Molecular Weight ]:
360.36100
[ Flash Point ]:
328.9ºC
[ Exact Mass ]:
360.13200
[ PSA ]:
139.12000
[ LogP ]:
2.01040
[ Vapour Pressure ]:
3.02E-16mmHg at 25°C
[ Index of Refraction ]:
1.651
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MC0500000
- CHEMICAL NAME :
- Glycine, N,N'-ethylenebis(2-(o-hydroxyphenyl)-
- CAS REGISTRY NUMBER :
- 1170-02-1
- BEILSTEIN REFERENCE NO. :
- 2679807
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C18-H20-N2-O6
- MOLECULAR WEIGHT :
- 360.40
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 175 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,1231,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 47 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB82-163692
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 53 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,292,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg/5D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in bladder weight Blood - other changes
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,292,1986
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3 gm/kg/5D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in spleen weight Endocrine - changes in thymus weight
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,292,1986
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1400 mg/kg/14D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in spleen weight Endocrine - changes in thymus weight
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,292,1986
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 168 mg/kg/14D-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,292,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2448 No. of Facilities: 13 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 264 (estimated) No. of Female Employees: 13 (estimated)
Safety Information
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%