(S)-(+)-2-AMino-3-cyclohexyl-1-propanol hydrochloride

Names

[ Name ]:
(S)-(+)-2-AMino-3-cyclohexyl-1-propanol hydrochloride

[Synonym ]:
(S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride
(2S)-2-amino-3-cyclohexylpropan-1-ol,hydrochloride
MFCD04972349

Chemical & Physical Properties

[ Density]:
0.97g/cm3

[ Boiling Point ]:
289.5ºC at 760mmHg

[ Melting Point ]:
230ºC (dec.)(lit.)

[ Molecular Formula ]:
C₉H₂₀ClNO

[ Molecular Weight ]:
193.71400

[ Flash Point ]:
128.9ºC

[ Exact Mass ]:
193.12300

[ PSA ]:
46.25000

[ LogP ]:
2.77870

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

H-Phe-ol
Methyl L-phenylalaninate hydrochloride
boc-beta-cyclohexyl-l-alaninol
L-Phenylalanine
Boc-L-phenylalanine methyl ester
Boc-Cha-OMe

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency.

J. Med. Chem. 31 , 2264, (1988)

The synthesis of diol-containing renin inhibitors has revealed that a simple vicinal diol functionality corresponding to the scissile Leu-Val bond in human angiotensinogen is capable of imparting inhi...

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