Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
2467.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀₉H₁₅₉N₂₅O₃₂S₅

[ Molecular Weight ]:
2491.902

[ Flash Point ]:
1446.0±34.3 °C

[ Exact Mass ]:
2490.018555

[ PSA ]:
1035.13000

[ LogP ]:
-0.36

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.556

[ Storage condition ]:
−20°C

[ Water Solubility ]:
1% acetic acid: >1 mg/mL | Soluble in water.

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+

[ RIDADR ]:
2811.0

[ WGK Germany ]:
3

[ RTECS ]:
KE9446500

[ Hazard Class ]:
6.1

ADP-ribosylation factor 6 regulates endothelin-1-induced lipolysis in adipocytes.

Biochem. Pharmacol. 90(4) , 406-13, (2014)

Endothelin-1 (ET-1) induces lipolysis in adipocytes, where ET-1 chronic exposure results in insulin resistance (IR) through suppression of glucose transporter (GLUT)4 translocation to the plasma membr...

HJP272, a novel endothelin receptor antagonist, attenuates lipopolysaccharide-induced acute lung injury in hamsters.

Lung 192(5) , 803-10, (2014)

Previous studies from this laboratory indicate that endothelin-1 (ET-1), a potent vasoconstrictor, may play an important role in lipopolysaccharide (LPS)-induced release of neutrophils from the pulmon...

Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase.

Biochem. Pharmacol. 94(2) , 91-100, (2015)

Important structural differences imply that human and mouse mast cell chymases may differ with respect to their enzymatic properties. We compared in this study the catalytic efficiencies of recombinan...

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