ICI 192605

Suppliers

Names

[ Name ]:
ICI 192605

[Synonym ]:
6-(2-(2-Chlorophenyl-4-hydroxyphenyl)-1,3-dioxan-5-yl)hexenoic acid
4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid
4-Hexenoic acid,6-(2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl)-,(2alpha,4alpha,5alpha(Z))
(4Z)-rel
4(Z)-6-(2,4,5-cis)-[(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hexenoic acid
(Z)-6-(-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl)hex-4-enoic acid
(4Z)-6-<(2RS,4RS,5SR)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl>hex-4-enoic acid

Chemical & Physical Properties

[ Density]:
1.262 g/cm3

[ Boiling Point ]:
540.1ºC at 760 mmHg

[ Molecular Formula ]:
C₂₂H₂₃ClO₅

[ Molecular Weight ]:
402.86800

[ Flash Point ]:
280.4ºC

[ Exact Mass ]:
402.12300

[ PSA ]:
75.99000

[ LogP ]:
5.25960

[ Vapour Pressure ]:
1.7E-12mmHg at 25°C

[ Index of Refraction ]:
1.583

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H410

[ Precautionary Statements ]:
P273-P501

[ RIDADR ]:
UN 3077 9 / PGIII

Articles

Thromboxane and isoprostane share the same prostanoid receptors to increase human placental tone

Placenta 32(12) , 941-8, (2011)

As the placenta is devoid of autonomic innervation, umbilical-placental vascular tone should be under the control of tissue and humoral factors. Among the numerous stimuli capable of challenging the p...

Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle.

Clin. Exp. Allergy 39(2) , 236-45, (2009)

Isoprostanes are prostaglandin (PG)-like compounds synthesized by oxidative stress, not by cyclooxygenase, and increase in bronchoalveolar lavage fluid of patients with asthma. The airway inflammation...

Endothelial thromboxane production plays a role in the contraction caused by 5-hydroxytryptamine in rat basilar arteries.

Eur. J. Pharmacol. 243(2) , 193-9, (1993)

The goal of the present study was to characterize the role of the endothelium in the 5-hydroxytryptamine (5-HT)-induced contraction of the rat basilar artery. Rat basilar artery segments were mounted ...