Ethanamine,2-[4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy]-N,N-diethyl-,hydrochloride (1:1)

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Names

[ CAS No. ]:
1178-99-0

[ Name ]:
Ethanamine,2-[4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy]-N,N-diethyl-,hydrochloride (1:1)

Chemical & Physical Properties

[ Density]:
1.091g/cm3

[ Boiling Point ]:
554.3ºC at 760 mmHg

[ Molecular Formula ]:
C₂₉H₃₄ClNO₂

[ Molecular Weight ]:
464.03900

[ Flash Point ]:
160.7ºC

[ Exact Mass ]:
463.22800

[ PSA ]:
21.70000

[ LogP ]:
7.12310

[ Vapour Pressure ]:
2.5E-12mmHg at 25°C

[ Index of Refraction ]:
1.587

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YE1660000

CHEMICAL NAME :: Triethylamine, 2-(p-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthyl)pheno xy)-, hydrochloride

CAS REGISTRY NUMBER :: 1178-99-0

LAST UPDATED :: 198910

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C29-H33-N-O2.Cl-H

MOLECULAR WEIGHT :: 464.09

WISWESSER LINE NOTATION :: L66 BUT&J BR DO2N2&2& CR& HO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 547 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 112,439,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 195 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 112,439,1963 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1240 ug/kg

SEX/DURATION :: female 3-4 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 112,439,1963

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1750 ug/kg

SEX/DURATION :: female 7 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,78,1967

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 500 ug/kg

SEX/DURATION :: female 10 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,78,1967

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3500 ug/kg

SEX/DURATION :: female 1 day(s) pre-mating female 1-6 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: CHINAG Chemistry and Industry (London). (Royal Soc. of Chemistry, Distribution Centre, Blackhorse Rd., Letchworth, Herts SG6 1HN, UK) V.1- 1923- Volume(issue)/page/year: (10),408,1963

Related Compounds

1-(1-Bromopropan-2-yl)-2-methoxy-4-methylbenzene
tert-butyl N-(4-oxo-1-phenylbutan-2-yl)carbamate
{[5-(2-Fluorophenyl)furan-2-yl]methyl}({2-[(morpholin-4-yl)methyl]phenyl}methyl)amine
3-(Piperidin-1-ylamino)-propionic acid methyl ester
2-chloro-N-[2-(2-methoxyphenoxy)ethyl]quinoline-4-carboxamide
2-(3-Methylfuran-2-yl)prop-2-enoic acid
1-[1-(4-fluorophenyl)-1H-imidazole-5-carbonyl]-4-(2-phenylethenesulfonyl)piperazine
N-(cyclohexylmethyl)butan-2-amine
4-bromo-2-fluoro-N-(2-hydroxyphenyl)benzamide
2-Methyl-2-(piperidin-1-yl)propanoic acid

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