Thiethylperazine dimaleate

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Names

[ CAS No. ]:
1179-69-7

[ Name ]:
Thiethylperazine dimaleate

[Synonym ]:
2-butenedioate
torecandimaleate
2-(Ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine (2Z)-but-2-enedioate (1:2)
Thiethylperazinbishydrogenmaleat
THIETHYLPERAZINE MALEATE (200 MG)
torecanmaleate
torecanbimaleate
thiethylperazine dimaleate
10H-Phenothiazine, 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-, (2Z)-2-butenedioate (1:2)
torecan
toresten
tresten
2-(Ethylsulfanyl)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (2Z)-2-butenedioate (1:2)
gs-95

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Boiling Point ]:
559.8ºC at 760 mmHg

[ Melting Point ]:
62-64ºC

[ Molecular Formula ]:
C30H37N3O8S2

[ Molecular Weight ]:
631.760

[ Flash Point ]:
292.4ºC

[ Exact Mass ]:
631.202209

[ PSA ]:
209.52000

[ LogP ]:
4.40320

[ Vapour Pressure ]:
1.46E-12mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SP0350000
CAS REGISTRY NUMBER :
1179-69-7
LAST UPDATED :
199504
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C22-H29-N3-S2.2C4-H4-O4
MOLECULAR WEIGHT :
631.82
WISWESSER LINE NOTATION :
T C666 BN ISJ ES2 B3- AT6N DNTJ D1 &OV1U1VO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,51,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,51,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
680 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,51,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
217 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MEXPAG Medicina Experimentalis. (Basel, Switzerland) V.1-11, 1959-64; V.18-19, 1968-69. For publisher information, see JNMDBO. Volume(issue)/page/year: 4,145,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
93 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MEXPAG Medicina Experimentalis. (Basel, Switzerland) V.1-11, 1959-64; V.18-19, 1968-69. For publisher information, see JNMDBO. Volume(issue)/page/year: 4,145,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1050 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,51,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
27 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,51,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5553 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 722 (estimated) No. of Female Employees: 377 (estimated)

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

  • THIETHYLPERAZINE MALATE (200 MG)
  • thiethylperazine
  • Afatinib dimaleate
  • Perazine Dimaleate
  • Pyrotinib dimaleate
  • (E)-but-2-enedioic acid,2-[2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethoxy]ethanol
  • Tert-butyl 4-[5-(aminomethyl)-2,4-dimethyl-3-(sulfanylmethyl)phenyl]piperazine-1-carboxylate
  • tert-butyl N-{6-hydroxy-2H-pyrazolo[3,4-b]pyridin-3-yl}carbamate
  • tert-butyl N-(3-cyano-4-hydroxythiophen-2-yl)carbamate
  • tert-butyl N-[3-(aminomethyl)-2-methyl-5-sulfanylphenyl]carbamate
  • 3-Iodo-2-methyl-5-(prop-2-yn-1-yl)aniline
  • Methyl 5-ethynyl-3-[(fluorosulfonyl)oxy]-2-methylbenzoate
  • (9H-fluoren-9-yl)methyl 4-[(5-amino-3-azido-2,4-dimethylphenyl)methyl]piperazine-1-carboxylate
  • (9H-fluoren-9-yl)methyl 4-[(3-ethynyl-2,4-dimethyl-5-sulfanylphenyl)methyl]piperazine-1-carboxylate
  • (9H-fluoren-9-yl)methyl 4-[(5-ethynyl-2,4-dimethyl-3-sulfanylphenyl)methyl]piperazine-1-carboxylate
  • Tert-butyl 4-({3-[(fluorosulfonyl)oxy]-2,4-dimethyl-5-(piperazin-1-yl)phenyl}methyl)piperazine-1-carboxylate