Tos-Gly-Pro-Arg-AMC · HCl

Names

[ CAS No. ]:
117961-27-0

[ Name ]:
Tos-Gly-Pro-Arg-AMC · HCl

[Synonym ]:
n-p-tosyl-gly-pro-arg 7-amido-4-methylcoumarin hydrochloride

Chemical & Physical Properties

[ Density]:
1.46g/cm3

[ Molecular Formula ]:
C₃₀H₃₈ClN₇O₇S

[ Molecular Weight ]:
676.18300

[ Exact Mass ]:
675.22400

[ PSA ]:
225.17000

[ LogP ]:
4.93230

[ Index of Refraction ]:
1.676

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Activating a zymogen without proteolytic processing: mutation of Lys15 and Asn194 activates trypsinogen.

Biochemistry 37(46) , 16201-10, (1998)

The zymogen and mature enzyme forms of trypsin-like serine proteases exhibit a wide range of activities. The prototypical trypsinogen-trypsin system is an example of a minimally active zymogen and a m...

[A photometric method of determining the activity of antithrombin III using a peptide coumarylamide substrate].

Lab. Delo (8) , 43-5, (1990)

Toz-Gly-Pro-Arg-4-methylcoumaryl-7-amide is recommended for antithrombin-III (AT-III) photometry as a substrate. This substrate is cleaved by thrombin at 366 nm. AT-III photometry with this substrate ...