1-Amino-7-naphthol

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Names

[ CAS No. ]:
118-46-7

[ Name ]:
1-Amino-7-naphthol

[Synonym ]:
8-Aminonaphthalen-2-ol
2-Naphthalenol, 8-amino-
8-amino-2-hydroxynapthalene
1-Amino-7-naphthol
8-amino-2-naphthaleno
8-Amino-naphthalen-2-ol
8-Amino-2-naphtol
8-Amino-2-napthol
MFCD00004031
8-amino-2-naphtho
AMINO-2-NAPHTHOL,8
CYANOL
1-amino-7-hydroxynaphthalene
EINECS 204-252-4
8-Amino-2-naphthol

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
378.3±17.0 °C at 760 mmHg

[ Melting Point ]:
206-210 °C(lit.)

[ Molecular Formula ]:
C10H9NO

[ Molecular Weight ]:
159.185

[ Flash Point ]:
182.6±20.9 °C

[ Exact Mass ]:
159.068420

[ PSA ]:
46.25000

[ LogP ]:
1.43

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.742

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL3331000
CHEMICAL NAME :
2-Naphthol, 8-amino-
CAS REGISTRY NUMBER :
118-46-7
BEILSTEIN REFERENCE NO. :
2207365
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H9-N-O
MOLECULAR WEIGHT :
159.20
WISWESSER LINE NOTATION :
L66J BZ IQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04024

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
QL3331000

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,7-cleve's acid
  • 8-nitronaphthalen-2-ol
  • 8-Nitronaphthalen-2-amine
  • Water

DownStream

  • acridino[2,1,9,8-klmna]acridine
  • 7-HYDROXY-1-NAPHTHONITRILE
  • 8-ACETAMIDONAPHTHALEN-2-YL ACETATE
  • 1-Acethyl amino-7 napththol
  • 8-Amino-1,2,3,4-tetrahydro-2-naphthalenol
  • 7-METHOXY-1-NAPHTHONITRILE
  • Agomelatine
  • 7-methoxy-1-Naphthaleneethanamine
  • 1-Methoxycarbonylamino-7-naphthol
  • 8-fluoronaphthalen-2-ol

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 1-Amino-7-naphthol
  • 1-amino-7-naphthol-3-sulphonic acid
  • 1-amino-7-allyloxy-2-naphthol
  • 1-amino-7,10-dibromo-4-hydroxy-2-methoxytetracene-5,12-dione
  • 1-amino-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
  • 1-Amino-7-[bis(2-chloroethyl)amino]-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid
  • 1-(3,4-dihydroquinolin-1(2H)-yl)-2-(1-(4-fluorobenzyl)-1H-indol-3-yl)ethanone
  • 4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1-(4-phenoxyphenyl)-1H-1,2,3-triazol-5-amine
  • N-(2-(6-oxopyridazin-1(6H)-yl)ethyl)-2-phenyl-2H-1,2,3-triazole-4-carboxamide
  • 6-Chloro-3,4-dihydro-1H-2-benzopyran-1-one
  • Globiferin
  • Thiazole, 5-bromo-2-cyclopentyl-
  • n-(3-Chloro-phenyl)-n-ethyl-2-piperidin-4-yl-acetamide
  • 4-(2-Bromophenyl)-2,4-Dioxobutanoic Acid
  • 4-(5-Amino-2-methylphenoxy)-2-pyridinecarboxamide
  • 2-(4-((1H-imidazol-1-yl)methyl)phenyl)acetic acid
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