4-Chloro-3,5-dinitrobenzoic acid

Names

[ CAS No. ]:
118-97-8

[ Name ]:
4-Chloro-3,5-dinitrobenzoic acid

[Synonym ]:
Benzoic acid, 4-chloro-3,5-dinitro-
EINECS 204-290-1
MFCD00007080
3,5-Dinitro-4-chlorobenzoic acid
4-Chloro-3,5-dinitrobenzoic acid

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
422.7±45.0 °C at 760 mmHg

[ Melting Point ]:
159-162 °C(lit.)

[ Molecular Formula ]:
C₇H₃ClN₂O₆

[ Molecular Weight ]:
246.561

[ Flash Point ]:
209.4±28.7 °C

[ Exact Mass ]:
245.967957

[ PSA ]:
128.94000

[ LogP ]:
2.03

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.666

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S28-S24/25-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Chlorobenzoic acid
4-Chloro-3-nitrobenzoic acid
Benzoic acid,4-amino-3,5-dinitro-
4-Bromo-3-nitrotoluene
4-Bromo-3,5-dinitrobenzoic acid
Benzenamine,4-methyl-2,6-dinitro-
4-bromo-3,5-dinitro-toluene
4,4'-DDA
Sulfuric acid
nitric acid

DownStream

4-Amino-3,5-dinitrobenzamide
2-Chloro-1,3-dinitrobenzene
Benzamide,4-chloro-3,5-dinitro-
3,5-Dinitrobenzoic acid
4-(dipropylamino)-3,5-dinitrobenzoic acid
Benzoic acid,4-chloro-3,5-dinitro-, methyl ester
1-chloro-2,6-dinitro-4-carboethoxybenzene
methyl 4-methoxy-3,5-dinitrobenzoate
4-DIMETHYLAMINO-3,5-DINITROBENZOIC ACID
Hemipyocyanine

Articles

The modulation of cytochrome c electron self-exchange by site-specific chemical modification and anion binding.

FEBS Lett. 206(1) , 15-9, (1986)

The site-specific chemical modification of horse heart cytochrome c at Lys-13 and -72 using 4-chloro-3,5-dinitrobenzoic acid (CDNB) increases the electron self-exchange rate of the protein. In the pre...

Localization of lysine residues in the binding domain of the K99 fibrillar subunit of enterotoxigenic Escherichia coli.

Biochim. Biophys. Acta 872(1-2) , 92-7, (1986)

Modification of lysine residues with 4-chloro-3,5-dinitrobenzoate results in the loss of the binding capacity of K99 fibrillae to horse erythrocytes (Jacobs, A.A.C., van Mechelen, J.R. and de Graaf, F...

Threshold levels in toxicology: significance of inactivation mechanisms.

Adv. Exp. Med. Biol. 136 Pt B , 1389-98, (1981)

Metabolic inactivation of chemicals may prevent toxic effects of reactive intermediates when present at low levels whereas inactivation may be overcome at high levels changing dose-effect relation. Th...

4-chloro-3,5-dinitrobenzoic acid ethyl ester
4-chloro-3,5-dinitrobenzoic acid methyl ester
4-chloro-3,5-dinitrobenzoic acid methyl ester
Methyl 4-Chloro-3,5-Dimethylbenzoate
4-CHLORO-3,5-DINITROPHENYLACETIC ACID
4-chloro-3,5-difluorobenzoic acid
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
{4-[(4-Bromophenyl)sulfonyl]-3-quinolyl}(piperidino)methanone
N-propyl-4-(1H-pyrrol-1-yl)picolinamide
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine