Zoledronic acid

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Names

[ CAS No. ]:
118072-93-8

[ Name ]:
Zoledronic acid

[Synonym ]:
zoledronate
Zoledronic acid monohydrate
P,P′-[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid monohydrate
acide [1-hydroxy-2-(1H-imidazol-1-yl)éthane-1,1-diyl]bis(phosphonique)
hydrogen [1-hydroxy-2-(1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
[1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid)
Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-
[1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)
Zometa,Zomera,Aclasta and Reclast
MFCD00867791
[1-Hydroxy-2-(1H-imidazol-1-yl)-ethylidene]bisphosphonic acid
[1-Hydroxy-2-(1H-imidazol-1-yl)ethan-1,1-diyl]bis(phosphonsäure)
Zoledronic acid
Phosphonic acid (P,P'-[1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic Acid
(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonic acid
2-(Imidazol-1-yl)-1-hydroxyethane-1,1-diphosphonic Acid
[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate

Chemical & Physical Properties

[ Density]:
2.1±0.1 g/cm3

[ Boiling Point ]:
764.0±70.0 °C at 760 mmHg

[ Melting Point ]:
193-2040ºC

[ Molecular Formula ]:
C5H10N2O7P2

[ Molecular Weight ]:
272.090

[ Flash Point ]:
415.8±35.7 °C

[ Exact Mass ]:
271.996338

[ PSA ]:
172.73000

[ LogP ]:
-2.28

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.719

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R21/22

[ Safety Phrases ]:
24/25-36/37/39

[ HS Code ]:
2933290090

Synthetic Route

Precursor & DownStream

Precursor

  • Imidazol-1-yl-acetic acid
  • imidazol-1-yl-acetyl chloride
  • zoledronate sodium
  • Phosphorus trichloride

DownStream

  • Zoledronic acid hydrate

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • Zoledronic acid
  • Zoledronic Acid-¹⁵N2,¹³C2
  • Zoledronic acid impurity A
  • Zoledronic acid trihydrate
  • zoledronic acid monosodium salt
  • Zoledronic Acid Related Compound
  • (9,9-Dimethyl-9H-xanthene-4,5-diyl)bis((3-(4-methoxyphenethyl)phenyl)(phenyl)phosphine)
  • N,N-Dibutyl-N-methylbutan-1-aminium 2,2-difluoroacetate
  • N,N-Dibutyl-N-methylbutan-1-aminium 3,5-Bis(trifluoromethyl)benzoate
  • 2-(Pyridin-2-yl)-4,5-di-p-tolyloxazole
  • (S)-2-((tert-Butoxycarbonyl)amino)-2-(4-methoxyphenyl)propanoic acid
  • (R)-Ethyl 4-(sec-butylamino)-6-chloronicotinate
  • (2S,3S)-Ethyl 2-(4-bromophenyl)tetrahydrofuran-3-carboxylate
  • 2-(Dimethylamino)-3,4-difluorobenzaldehyde
  • 6-(Aminomethyl)-4-methoxy-7H,8H-pyrido[2,3-d]pyrimidin-7-one
  • [2-(3-Ethoxyphenyl)ethynyl]trimethylsilane
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