L-365,260

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Names

[ CAS No. ]:
118101-09-0

[ Name ]:
L-365,260

[Synonym ]:
L-365,260,N-[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)urea
L-365260

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
611.5ºC at 760 mmHg

[ Molecular Formula ]:
C24H22N4O2

[ Molecular Weight ]:
398.45700

[ Flash Point ]:
323.6ºC

[ Exact Mass ]:
398.17400

[ PSA ]:
73.80000

[ LogP ]:
3.92110

[ Vapour Pressure ]:
6.85E-15mmHg at 25°C

[ Index of Refraction ]:
1.648

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H400

[ Precautionary Statements ]:
P273-P301 + P310

[ RIDADR ]:
UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all

Articles

Combination pharmacotherapy for the treatment of neuropathic pain in adults.

Cochrane Database Syst. Rev. 7 , CD008943, (2012)

Pharmacotherapy remains an important modality for the treatment of neuropathic pain. However, as monotherapy current drugs are associated with limited efficacy and dose-related side effects. Combining...

Modeled structure of a G-protein-coupled receptor: the cholecystokinin-1 receptor.

J. Med. Chem. 48(1) , 180-91, (2005)

The Cholecystokinin-1 receptor (CCK1R) mediates actions of CCK in areas of the central nervous system and of the gut. It is a potential target to treat a number of diseases. As for all G-protein-coupl...

A cholecystokinin-1 receptor agonist (CCK-8) mediates increased permeability of brain barriers to leptin.

Br. J. Pharmacol. 154(5) , 1009-15, (2008)

Leptin regulates energy expenditure and body weight by acting both on the hypothalamus and on peripheral targets. Central actions of leptin are enhanced by cholecystokinin (CCK). The interaction betwe...


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Related Compounds

  • Cyclo(L-isoleucyl-D-2,3,4,5-tetrahydro-3-pyridazinecarbonyl-L-2,3,4,5-tetrahydro-3-pyridazinecarbonyl-N-methyl-D-phenylalanyl-L-prolyl-D-phenylalanyl
  • 4-bromo-N-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)benzamide
  • L-lysine acetate
  • L-arginine monothiazolidine-4-carboxylate
  • L-Arginine-L-pyroglutamate
  • L-Lysine monoacetate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • N-(2-methoxyethyl)-N-(thiophen-3-ylmethyl)benzo[b]thiophene-2-carboxamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4'-Iodo-3'-(trifluoromethyl)acetophenone
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • (E)-3-(furan-3-yl)-N-(2-hydroxy-2-(1-methylindolin-5-yl)ethyl)acrylamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde