Icaritin

Suppliers

Names

[ Name ]:
Icaritin

[Synonym ]:
3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
Icaritin
3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
BIDD:ER0021
4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
3,7-dihydroxy-8-prenyl-4'-methoxychrysin
Anhydroicaritin

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
582.0±50.0 °C at 760 mmHg

[ Melting Point ]:
239ºC

[ Molecular Formula ]:
C₂₁H₂₀O₆

[ Molecular Weight ]:
368.380

[ Flash Point ]:
206.7±23.6 °C

[ Exact Mass ]:
368.125977

[ PSA ]:
100.13000

[ LogP ]:
4.84

[ Appearance of Characters ]:
light yellow to dark yellow

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.657

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: soluble5mg/mL, clear (warmed)

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DJ3100870

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Icariin
Epimedin A
Sagittatoside A

DownStream

Articles

Icaritin ameliorates carbon tetrachloride-induced acute liver injury mainly because of the antioxidative function through estrogen-like effects.

In Vitro Cell. Dev. Biol. Anim. 50(10) , 899-908, (2014)

To investigate the effects of icaritin, an active ingredient extracted from Epimedium Sagittatum (Sieb. et Zucc.), on CCl4-induced liver injury and its possible mechanisms. Hepatocytes isolated from S...

Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma.

J. Exp. Clin. Cancer Res 34 , 17, (2015)

Extranodal NK/T-cell lymphoma (ENKL) is an aggressive hematological malignancy associated with Epstein-Barr virus (EBV) infection. It is often resistant to conventional chemotherapy and has a poor pro...

Icaritin, an exogenous phytomolecule, enhances osteogenesis but not angiogenesis--an in vitro efficacy study.

PLoS ONE 7 , e41264, (2012)

We found that Icaritin, an intestinal metabolite of Epimedium-derived flavonoids (EF) enhanced osteoblastic differentiation of mesenchymal stem cells (MSCs) only under osteogenic induction conditions....

Noricaritin
Noranhydroicaritin
3,7-BIS(2-HYDROXYETHYL)ICARITIN
DesMethyl Icaritin Tri-O-MethoxyMethyl Ether
N-(2-hydroxyphenyl)-2-(methylsulfanyl)pyridine-3-carboxamide
5-Bromo-2-fluoro-N-((4-methylthiazol-2-yl)methyl)benzamide
3,5-difluoro-N-(6-methylpyridin-2-yl)benzamide
4-Methyl-6-(p-tolylthio)pyrimidin-2-amine
N-(3-Cyanophenyl)-1-cyclopropyl-5-oxo-3-pyrrolidinecarboxamide
N-[[5-(4-Bromophenyl)-2-furanyl]methyl]-4-[(2,2-dimethyl-1-oxopropyl)amino]butanamide
1-(2-methylpropanoyl)-N-phenylpiperidine-4-carboxamide
N-[4-(4-Fluorophenyl)-2-thiazolyl]-2-cyclopentene-1-acetamide
N-(1-cyanocycloheptyl)-2-[4-(2,5-difluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide
N-[2-(3-chlorophenyl)ethyl]-4-ethyl-1,2,3-thiadiazole-5-carboxamide

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