Trametinib (DMSO solvate)

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Names

[ CAS No. ]:
1187431-43-1

[ Name ]:
Trametinib (DMSO solvate)

[Synonym ]:
Trametinib DMSO
Mekinist
trametinib dimethyl sulfoxide
Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compd. with 1,1'-sulfinylbis[methane] (1:1)
Trametinib DMSO solvate
N-(3-{3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide - (methylsulfinyl)methane (1:1)
UNII-BSB9VJ5TUT
GSK1120212B
N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide,methylsulfinylmethane
Trametinib (DMSO solvate)

Chemical & Physical Properties

[ Molecular Formula ]:
C28H29FIN5O5S

[ Molecular Weight ]:
693.528

[ Exact Mass ]:
693.091797

[ PSA ]:
146.90000

[ LogP ]:
5.52300

[ Storage condition ]:
2-8℃

Related Compounds

  • Trametinib-13C,d3
  • Trametinib (GSK1120212)
  • [Os(DMSO)2(CN)2(2,2'-bipyridine)]
  • [Os(DMSO)2(CN)2(4,4'-di-tert-butyl-2,2'-bipyridine)]
  • RuCl2(DMSO)4
  • [Os(DMSO)2(CN)2(2,2'-bipyridine)]*MeOH
  • 2-{[(Tert-butoxy)carbonyl](methyl)amino}-4,4-difluorobutanoic acid
  • 1-ethyl-5-[(3-methoxyazetidin-3-yl)methyl]-1H-imidazole
  • 2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid
  • 1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-2-carbonyl]-6-methylpiperidine-3-carboxylic acid
  • 3-(piperidin-4-yloxy)-1H-indole
  • 1-(2,5-Dimethoxybenzyl)azetidine
  • 3-(5-Bromothiophen-3-yl)-2-hydroxy-3-methylbutanoic acid
  • 6-(3-Phenylphenyl)pyridine-3-carbaldehyde
  • tert-butyl N-[4-(2-amino-1,1-difluoroethyl)cyclohexyl]carbamate
  • [2-(5-methyl-1H-indazol-6-yl)piperidin-4-yl]methanamine
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