Benzoin

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Names

[ CAS No. ]:
119-53-9

[ Name ]:
Benzoin

[Synonym ]:
(RS)-Benzoin
(±)-2-Hydroxy-2-phenylacetophenone
Ethanone, 2-hydroxy-1,2-diphenyl-
Chc11,Benzoin
(±)-2-Hydroxy-1,2-diphenylethanone
AURORA KA-7034
2-hydroxy-1,2-diphenyl ethanone
Persian balsam
α-Hydroxybenzyl Phenyl Ketone
α-Hydroxy-α-phenylacetophenone
Benzoin Zone Refined
2-Hydroxy-1,2-diphenylethanone
FEMA 2132
EINECS 204-331-3
1,2-diphenyl-2-hydroxyethanone
(±)-Benzoin
MFCD00004496
Ketone, α-hydroxybenzyl phenyl
DL-BENZOIN
Nisso Cure MB
desyl alcohol
BENZOIN GUM
1,2-Diphenyl-1-hydroxy-2-ethanone
Benzoin
2-Hydroxy-2-phenylacetophenone

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
343.0±0.0 °C at 760 mmHg

[ Melting Point ]:
134-138 °C(lit.)

[ Molecular Formula ]:
C14H12O2

[ Molecular Weight ]:
212.244

[ Flash Point ]:
154.8±14.9 °C

[ Exact Mass ]:
212.083725

[ PSA ]:
37.30000

[ LogP ]:
2.13

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.609

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DI1590000
CHEMICAL NAME :
Benzoin
CAS REGISTRY NUMBER :
119-53-9
BEILSTEIN REFERENCE NO. :
0391839
LAST UPDATED :
199710
DATA ITEMS CITED :
24
MOLECULAR FORMULA :
C14-H12-O2
MOLECULAR WEIGHT :
212.26
WISWESSER LINE NOTATION :
QYR&VR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
8870 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
DNA damage
TYPE OF TEST :
Unscheduled DNA synthesis
TYPE OF TEST :
Unscheduled DNA synthesis

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
500 mg/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 13,133,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80585 No. of Facilities: 2083 (estimated) No. of Industries: 25 No. of Occupations: 30 No. of Employees: 151846 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9855 No. of Facilities: 6 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 42 (estimated) No. of Female Employees: 18 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80585 No. of Facilities: 189 (estimated) No. of Industries: 4 No. of Occupations: 16 No. of Employees: 26840 (estimated) No. of Female Employees: 22514 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
DI1590000

[ HS Code ]:
2914400090

Synthetic Route

Precursor & DownStream

Precursor

  • Benzil
  • Benzaldehyde
  • trans-Stilbene
  • hydrobenzoin
  • meso-1,2-Diphenyl-1,2-ethanediol
  • Benzyl alcohol
  • acrylic acid methyl ester
  • Formaldehyde
  • (+/-)-HYDROBENZOIN

DownStream

  • Erbium(III) Ionophore I
  • 2-amino-4,5-diphenyl-3-furonitrile
  • Glycerol, tribenzoate
  • 4,4'-azobisbenzoic acid
  • 2-AMINO-4-METHYLBENZOPHENONE
  • Methyl benzoin
  • (Z)-α,α'-dimethoxystilbene
  • 2-methoxy-1,2-diphenylpropan-1-one
  • 1-Propanone,2-hydroxy-1,2-diphenyl-

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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Related Compounds

  • benzoin
  • benzoin
  • benzoin
  • DL-Benzoin
  • Benzoin,(+)
  • benzoin-d10
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 3-methyl-6-phenyl-N-(pyridin-3-yl)imidazo[2,1-b]thiazole-2-carboxamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide