3,3'-Dimethoxybiphenyl-4,4'-diamine
Suppliers
Names
[ CAS No. ]:
119-90-4
[ Name ]:
3,3'-Dimethoxybiphenyl-4,4'-diamine
[Synonym ]:
[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-
3,3'-Dimethoxy-4,4'-diaminodiphenyl
3,3'-Dimethoxybenzidine
3,3‘-Dimethoxybenzidine
3,3'-Dimethoxy-4,4'-biphenyldiamine
4,4'-Diamino-3,3'-dimethoxybiphenyl
EINECS 204-355-4
3,3'-Dimethoxy-[1,1'-biphenyl]-4,4'-diamine
3,3'-Dimethoxybiphenyl-4,4'-diamine
Fast Blue B
3,3-Dimethoxybenzidine
MFCD00008372
o-dianisidine
4-(4-amino-3-methoxyphenyl)-2-methoxyaniline
3,3′-Dimethoxybenzidine
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
391.3±37.0 °C at 760 mmHg
[ Melting Point ]:
137-138 °C(lit.)
[ Molecular Formula ]:
C14H16N2O2
[ Molecular Weight ]:
244.289
[ Flash Point ]:
206.1±0.0 °C
[ Exact Mass ]:
244.121185
[ PSA ]:
70.50000
[ LogP ]:
1.58
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.619
[ Water Solubility ]:
H2O: slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DD0875000
- CHEMICAL NAME :
- Benzidine, 3,3'-dimethoxy-
- CAS REGISTRY NUMBER :
- 119-90-4
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 36
- MOLECULAR FORMULA :
- C14-H16-N2-O2
- MOLECULAR WEIGHT :
- 244.32
- WISWESSER LINE NOTATION :
- 1OR BZ ER DZ CO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1920 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 gm/kg/56W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 588 gm/kg/70W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TYPE OF TEST :
- Cytogenetic analysis
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - dog Cells - not otherwise specified
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1893,1984 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,41,1974 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,198,1987 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,198,1987 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-SWEDEN;Carcinogen JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO o-DIANISIDINE-BASED DYES-air:CA lowest feasible conc. REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80274 No. of Facilities: 49 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 122 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80274 No. of Facilities: 92 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 2481 (estimated) No. of Female Employees: 866 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H350
[ Precautionary Statements ]:
P201-P308 + P313
[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R45;R22
[ Safety Phrases ]:
S53-S45
[ RIDADR ]:
2811
[ WGK Germany ]:
3
[ RTECS ]:
DD0875000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2922299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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