Glimepiride sulfonamide

Suppliers

Names

[ CAS No. ]:
119018-29-0

[ Name ]:
Glimepiride sulfonamide

[Synonym ]:
3-Ethyl-4-methyl-2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2,5-dihydro-1H-pyrrole-1-carboxamide
SulfonamideofGlimepiride
1H-Pyrrole-1-carboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-3-ethyl-2,5-dihydro-4-methyl-2-oxo-
MFCD08460214
GliMepiride Related CoMpound B
EINECS 411-850-0
Glimepiride sulfonamide
3-Ethyl-4-methyl-2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2,5-dihydro-1H-pyrrol-1-carboxamid
4-[2-(3-ethyl-4-methyl-2-oxy-3-pyrrolinyl-1-methylamide)-ethyl]benzenesulfonamide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
177-179?C

[ Molecular Formula ]:
C16H21N3O4S

[ Molecular Weight ]:
351.421

[ Exact Mass ]:
351.125275

[ PSA ]:
117.95000

[ LogP ]:
0.43

[ Index of Refraction ]:
1.588

[ Storage condition ]:
Refrigerator

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R52/53

[ Safety Phrases ]:
61

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-{2-{[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)-carbonyl]-amino}-ethyl}-benzenesulfonyl chloride
  • ethyl 3-cyano-2-ethyl-3-hydroxybutanoate
  • Ethyl 2-ethyl-3-oxobutanoate
  • 3-Ethyl-4-methyl-3-pyrrolin-2-one
  • 1-acetyl-3-ethyl-4-Methyl-1H-pyrrol-2(5H)-one
  • 2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-FURO[3,2-B]PYRIDINE-6-CARBONITRILE

DownStream

  • Glimepiride

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Simultaneous determination of Glimepiride and Metformin hydrochloride impurities in sustained release pharmaceutical drug product by HPLC. Pawar, Shraddha, et al.

Der Pharma Chemica 2.4 , 157-168, (2010)


More Articles

Related Compounds

  • 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide,5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione,hydrochloride
  • Glimepiride
  • Glimepiride-d4-1
  • glimepiride related compound c (20 mg) (glimepiride urethane)
  • Glimepiride-d5
  • Glimepiride-d4(phenylethyl-α,α,β,β-d4)(cis/trans)