Dabrafenib Mesylate

Suppliers

Names

[ CAS No. ]:
1195768-06-9

[ Name ]:
Dabrafenib Mesylate

[Synonym ]:
Benzenesulfonamide, N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-, methanesulfonate (1:1)
N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide,methanesulfonic acid
Tafinlar
N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(2-methyl-2-propanyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide methanesulfonate (1:1)
N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide methanesulfonate (1:1)
UNII-B6DC89I63E
N-{3-[5-(2-aminopyrimidin-4-yl)-2-(1,1-dimethylethyl)thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide monomethanesulfonate
dabrafenib mesylate
GSK-2118436B
Dabrafenib (Mesylate)

Chemical & Physical Properties

[ Molecular Formula ]:
C24H24F3N5O5S3

[ Molecular Weight ]:
615.668

[ Exact Mass ]:
615.089172

[ PSA ]:
210.96000

[ LogP ]:
7.03360

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanesulfonic acid
  • Dabrafenib
  • 2,6-Difluorobenzenesulfonyl chloride
  • Methyl 3-amino-2-fluorobenzoate
  • Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate
  • N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-diethylethyl)-1,3-thiazol-4-yl]-2-fluoraphenyl}-2,6-difluorobenzenesulfonamide

DownStream

Related Compounds

  • Dabrafenib-d9
  • Dabrafenib
  • BPR1R024 mesylate
  • Tropisetron mesylate
  • TVP1022 (mesylate)
  • Alatrofloxacin Mesylate
  • 9-(3,5-Dimethoxyphenyl)-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-2-benzo[h][1,6]naphthyridinone
  • benzyl N-(4-hydroxy-1-methylcyclohexyl)carbamate
  • Cyclobutyl(cyclopentyl)methanamine
  • 4-(Pyridin-3-yl)pyrrolidin-3-ol
  • 1-(3,5-difluorobenzyl)-1H-pyrrole-3-carboxylic acid
  • 4-(But-3-yn-1-ylamino)picolinic acid
  • 1-(3-Bromo-4-methylphenyl)ethane-1,2-diol
  • 2-amino-N-(but-3-yn-1-yl)benzamide
  • 1-(3,5-Difluorobenzyl)pyrrolidine-3-carboxylic acid
  • tert-butyl N-{[(4-ethylphenyl)carbamoyl]methyl}carbamate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.