2 4-DIAMINO-5-IODOQUINAZOLINE

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Names

[ CAS No. ]:
119584-76-8

[ Name ]:
2 4-DIAMINO-5-IODOQUINAZOLINE

[Synonym ]:
iodoquinazolinediamine
2,4-diamino-5-iodoquinazoline
5-Iodo-2,4-quinazolinediamine
2,4-Quinazolinediamine,5-iodo

Chemical & Physical Properties

[ Density]:
2.093g/cm3

[ Boiling Point ]:
527.9ºC at 760mmHg

[ Molecular Formula ]:
C₈H₇IN₄

[ Molecular Weight ]:
286.07200

[ Flash Point ]:
273ºC

[ Exact Mass ]:
285.97200

[ PSA ]:
77.82000

[ LogP ]:
2.56120

[ Vapour Pressure ]:
3.13E-11mmHg at 25°C

[ Index of Refraction ]:
1.862

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA1367760

CHEMICAL NAME :: 2,4-Quinazolinediamine, 5-iodo-

CAS REGISTRY NUMBER :: 119584-76-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H7-I-N4

MOLECULAR WEIGHT :: 286.09

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,434,1990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Carbonic acid-guanidine (1:2)
2-Fluoro-6-iodobenzonitrile
2-aMino-6-iodobenzonitrile
Chloroformamidine hydrochloride
carbonic acid; guanidine
2,6-Dinitrobenzonitrile
2-AMINO-6-NITROBENZONITRILE
2-iodo-6-nitrobenzonitrile
2-Chloro-1,3-dinitrobenzene
2,6-Difluorobenzonitrile

DownStream

Related Compounds

2,4-DIAMINO-5-FLUOROTOLUENE
2,4-Diamino-5-quinazolinecarbonitrile
2,4-Diamino-5,6-dihydropyrido[2,3-d]pyrimidin-7(1H)-one
(2,4-diamino-5,6,7,8-tetrahydro-quinazolin-6-yl)-methanol
2,4-diamino-5-hydroxy-6-methylpyrimidine hydrochloride
2,4-Diamino-5-(1,2,3,4-tetrahydro-N-methyl-6-quinolylmethyl)pyrimidine