Indole-5-carboxaldehyde

Names

[ CAS No. ]:
1196-69-6

[ Name ]:
Indole-5-carboxaldehyde

[Synonym ]:
MFCD02093664
5-Formylindole
1H-Indole-5-carboxaldehyde
Indole-5-carboxaldehyde
1H-Indole-5-carbaldehyde

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
339.1±15.0 °C at 760 mmHg

[ Melting Point ]:
100-103 °C(lit.)

[ Molecular Formula ]:
C₉H₇NO

[ Molecular Weight ]:
145.158

[ Flash Point ]:
166.8±27.8 °C

[ Exact Mass ]:
145.052765

[ PSA ]:
32.86000

[ LogP ]:
1.56

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.729

[ Storage condition ]:
Keep Cold

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

5-METHYL-1-PROPYL-1H-PYRAZOL-3-AMINE
1-Methyl-1H-indole-5-carbaldehyde
5-(2-nitroethenyl)-1H-indole
1-Benzylindole-5-carboxaldehyde
Indole-5-Methanol
2-(1H-indol-5-yl)-1H-benzimidazole
TERT-BUTYL 5-FORMYL-1H-INDOLE-1-CARBOXYLATE
5-Cyanoindole
5-ethenyl-1H-indole
1-PHENYLSULFONYLINDOLE-5-ALDEHYDE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and antifungal activity of novel streptochlorin analogues.

Eur. J. Med. Chem. 92 , 776-83, (2015)

Streptochlorin, first isolated as a new antibiotic in 1988 from the lipophilic extracts of the mycelium of a Streptomyces sp, is an indole natural products with a variety of biological activities. Bas...

Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization.

Bioorg. Med. Chem. 19 , 4782-95, (2011)

We previously reported the discovery of 2-aryl-4-benzoyl-imidazoles (ABI-I) as potent antiproliferative agents for melanoma. To further understand the structural requirements for the potency of ABI an...

Synthesis and biological evaluation of achiral indole-substituted titanocene dichloride derivatives.

Int J Med Chem 2012 , 905981, (2015)

Six new titanocene compounds have been isolated and characterised. These compounds were synthesised from their fulvene precursors using Super Hydride (LiBEt3H) followed by transmetallation with titani...