BiCAPPA

Names

[ CAS No. ]:
119662-55-4

[ Name ]:
BiCAPPA

[Synonym ]:
BiCAPPA
N,N inverted exclamation marka-Bis(6-chloro-2-methoxy-9-acridinyl)-1,4-piperazinedipropanamine
N,N'-Bis(6-chloro-2-methoxy-9-acridinyl)-1,4-piperazinedipropanamine

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₈H₄₀Cl₂N₆O₂

[ Molecular Weight ]:
683.66900

[ Exact Mass ]:
682.25900

[ PSA ]:
81.24000

[ LogP ]:
7.05480

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Articles

Protein aggregation and neurodegenerative disease.

Nat. Med. 10 Suppl , S10-S17 , (2004)

Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and prion diseases are increasingly being realized...

Potent inhibition of scrapie prion replication in cultured cells by bis-acridines.

Proc. Natl. Acad. Sci. U. S. A. 100 , 3416-3421, (2003)

Prion diseases are characterized by an accumulation of PrP(Sc), a misfolded isoform of the normal cellular prion protein, PrP(C). We previously reported the bioactivity of acridine-based compounds aga...