6-O-Methyl-2',4''-bis-O-(trimethylsilyl)erythromycin 9-[O-(1-ethoxy-1-methylethyl)oxime]

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Names

[ CAS No. ]:
119699-81-9

[ Name ]:
6-O-Methyl-2',4''-bis-O-(trimethylsilyl)erythromycin 9-[O-(1-ethoxy-1-methylethyl)oxime]

[Synonym ]:
Erythromycin, 6-O-Methyl-2',4'-Bis-O-(Trimethylsilyl)-, 9-[O-(1-Methoxy-1-Methylethyl)Oxime]

Chemical & Physical Properties

[ Density]:
1.115g/cm3

[ Boiling Point ]:
838.422ºC at 760 mmHg

[ Molecular Formula ]:
C48H94N2O14Si2

[ Molecular Weight ]:
979.43600

[ Flash Point ]:
460.861ºC

[ Exact Mass ]:
978.62400

[ PSA ]:
174.66000

[ LogP ]:
7.34410

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.499

Synthetic Route

Precursor & DownStream

Precursor

  • silylated erythromycin oxime ketal
  • methyl iodide
  • Dimethyl sulfate

DownStream

  • Clarithromycin

Related Compounds

  • 1-(Ethoxycarbonyl)-3,4-dimethylcyclohexane-1-carboxylic acid
  • 1-Tert-butyl-4-(ethoxycarbonyl)piperidine-4-carboxylic acid
  • rac-(2R,3S)-5-oxo-3-phenyl-4-(propan-2-yl)-1-(2,2,2-trifluoroacetyl)piperazine-2-carboxylic acid
  • 1-(Ethoxycarbonyl)-3-ethylcyclohexane-1-carboxylic acid
  • 3-(Ethoxycarbonyl)bicyclo[3.2.1]octane-3-carboxylic acid
  • 4-{[(9H-fluoren-9-yl)methoxy]carbonyl}thiomorpholine-2-carboxylic acid
  • 2-(1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-methylpiperidin-3-yl)acetic acid
  • 1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-methyl-1,4-diazepane-6-carboxylic acid
  • 4-{[(9H-fluoren-9-yl)methoxy]carbonyl}-1-oxo-1lambda4-thiomorpholine-3-carboxylic acid
  • tert-butyl N-(4-cyclobutyl-3-methyl-4-oxobutan-2-yl)carbamate
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