Phentermine Hydrochloride
Suppliers
Names
[ CAS No. ]:
1197-21-3
[ Name ]:
Phentermine Hydrochloride
[Synonym ]:
MFCD00058289
2-methyl-1-phenylpropan-2-amine,hydrochloride
Phentermine Hydrochloride
EINECS 214-821-9
Chemical & Physical Properties
[ Boiling Point ]:
206ºC at 760mmHg
[ Melting Point ]:
200-201℃
[ Molecular Formula ]:
C10H16ClN
[ Molecular Weight ]:
185.69400
[ Flash Point ]:
93.1ºC
[ Exact Mass ]:
185.09700
[ PSA ]:
26.02000
[ LogP ]:
3.46870
[ Vapour Pressure ]:
0.243mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH4950000
- CHEMICAL NAME :
- Phenethylamine, alpha,alpha-dimethyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 1197-21-3
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H15-N.Cl-H
- MOLECULAR WEIGHT :
- 185.72
- WISWESSER LINE NOTATION :
- ZX1&1&1R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 188 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,256,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 81 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 17,121,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 154 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,256,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,187,1943
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301
[ Precautionary Statements ]:
Missing Phrase - N15.00950417
[ Hazard Codes ]:
T: Toxic;Xi: Irritant;
[ Risk Phrases ]:
R25
[ Safety Phrases ]:
S22-S26-S36/37-S45
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
SH4950000
[ HS Code ]:
2921499090
Synthetic Route
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%