1-(5'-trityl-2',3'-dideoxy-3'-toluenesulfonyl-β-D-glyceropent-2-enofuranosyl)uracil

Names

[ CAS No. ]:
119753-91-2

[ Name ]:
1-(5'-trityl-2',3'-dideoxy-3'-toluenesulfonyl-β-D-glyceropent-2-enofuranosyl)uracil

Chemical & Physical Properties

[ Molecular Formula ]:
C35H30N2O6S

[ Molecular Weight ]:
606.68700

[ Exact Mass ]:
606.18200

[ PSA ]:
115.84000

[ LogP ]:
6.18970

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(5'-O-trityl-3'-deoxy-3'-toluenesulfonyl-β-D-arabinofuranosyl)uracil
  • 1-[2,3-epoxy-5-O-(triphenylmethyl)-β-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione
  • 1-(5'-O-trityl-3'-deoxy-3'-(4-toluene)thio-β-D-arabinofuranosyl)uracil
  • 1-[2,3-di-O-(metanesulfonyl)-5-O-(triphenylmethyl)-β-D-ribofuranosyl]pyrimidine-2,4(1H,3H)-dione

DownStream

  • 1-[(2R,3R,5S)-5-(hydroxymethyl)-3-piperidin-1-yloxolan-2-yl]pyrimidine-2,4-dione
  • 1-[(2R,3R,5S)-5-(hydroxymethyl)-3-morpholin-4-yloxolan-2-yl]pyrimidine-2,4-dione
  • 1-((2R,3R,5S)-3-(pyrrolidin-1-yl)-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 1-((2R,3R,5S)-3-(piperidin-1-yl)-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 1-((2R,3R,5S)-3-morpholino-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione