Grepafloxacin
Suppliers
Names
[ CAS No. ]:
119914-60-2
[ Name ]:
Grepafloxacin
[Synonym ]:
1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-cyclopropyl-5-methyl-6-fluoro-7-(3-methylpiperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-7-(3-methyl-1-piperazinyl)-5-methyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
MFCD00865116
Chemical & Physical Properties
[ Density]:
1.366
[ Boiling Point ]:
610ºC at 760mmHg
[ Melting Point ]:
189-192ºC
[ Molecular Formula ]:
C19H22FN3O3
[ Molecular Weight ]:
359.39500
[ Flash Point ]:
322.7ºC
[ Exact Mass ]:
359.16500
[ PSA ]:
74.57000
[ LogP ]:
2.67400
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VB1993785
- CHEMICAL NAME :
- 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-5-methyl-7-(3-meth yl- 1-piperazinyl)-4-oxo-
- CAS REGISTRY NUMBER :
- 119914-60-2
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C19-H22-F-N3-O3
- MOLECULAR WEIGHT :
- 359.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 78 mg/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 22,4531,1994
Safety Information
[ Hazard Codes ]:
Xi