CAY10621(SKI 5C)

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Names

[ CAS No. ]:
120005-55-2

[ Name ]:
CAY10621(SKI 5C)

[Synonym ]:
2-Methyl-2-propanyl (4S)-4-(2-hexadecynoyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-(1-oxo-2-hexadecyn-1-yl)-, 1,1-dimethylethyl ester, (4S)-
z-n-e-boc-l-lysine amide

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
519.0±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H45NO4

[ Molecular Weight ]:
435.640

[ Flash Point ]:
267.7±32.9 °C

[ Exact Mass ]:
435.334869

[ PSA ]:
55.84000

[ LogP ]:
8.67

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.478

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Pentadecyne
  • (S)-3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID
  • (4S,1'R)-4-(1'-Hydroxy-2'-hexadecinyl)-2,2-dimethyl-3-oxazolidincarbonsaeure-tert-butylester
  • 4,8-dicyano-1,2,4,8-tetramethyl-3,9-dioxatricyclo-[5.2.1.02,6]decane
  • (s)-(-)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyl-1,3-oxazolidine
  • Boc-Ser-OH
  • BOC-ON
  • Boc-Ser-OMe
  • (R)-3-tert-butyl 4-methyl 2,2-dimethyloxazolidine-3,4-dicarboxylate

DownStream

  • D-erythro-Sphingosine

Articles

Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG1 axis in hepatocellular carcinoma.

Liver Int. 32(2) , 331-8, (2012)

Sphingosine kinase 1 (SphK1), which phosphorylates sphingosine to sphingosine-1-phosphate (S1P), is overexpressed in various types of cancers, and may act as an oncogene in tumorigenesis. However, lit...


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Related Compounds

  • RU-SKI 43
  • Bosutinib (SKI-606)
  • 3,3,5c-trimethyl-cyclohexan-r-ol
  • (+/-)-2c,5c-dimethyl-cyclohexane-r-carboxylic acid
  • 4-methyl-5c-phenyl-2-thioxo-oxazolidine-3,4r-dicarboxylic acid diethyl ester
  • 2,3c,5c,6t-tetramethyl-[1,4]dioxane-2r,5t-diol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • N-cyclohexyl-1-methyl-pyrazol-3-amine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 1-(2,4-Difluorophenyl)-3-ethoxypropan-2-one
  • tert-Butyl-DL-alanine