2-[(2-nitroimidazol-1-yl)methoxy]propane-1,3-diol

Names

[ CAS No. ]:
120398-89-2

[ Name ]:
2-[(2-nitroimidazol-1-yl)methoxy]propane-1,3-diol

[Synonym ]:
rp-170

Chemical & Physical Properties

[ Density]:
1.56g/cm3

[ Boiling Point ]:
523.2ºC at 760 mmHg

[ Molecular Formula ]:
C7H11N3O5

[ Molecular Weight ]:
217.17900

[ Flash Point ]:
270.2ºC

[ Exact Mass ]:
217.07000

[ PSA ]:
113.33000

[ Vapour Pressure ]:
8.99E-12mmHg at 25°C

[ Index of Refraction ]:
1.608

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ0819000
CHEMICAL NAME :
1,3-Propanediol, 2-((2-nitro-1H-imidazol-1-yl)methoxy)-
CAS REGISTRY NUMBER :
120398-89-2
LAST UPDATED :
199409
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H11-N3-O5
MOLECULAR WEIGHT :
217.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #91-209323
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 80,1113,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
4300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTKRDX Gan to Kagaku Ryoho. Cancer and Chemotherapy. (1-8-9 Yaesu, Chuo-ku, Tokyo 103, Japan) V.1- 1974- Volume(issue)/page/year: 16,1399,1989

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-[2-acetoxy-1-(acetoxymethyl)ethoxy]methyl-2-nitroimidazol

DownStream

Related Compounds

  • 2-methyl-2-prop-2-ynylpropane-1,3-diol
  • 2-[(2-nitroimidazol-1-yl)methoxy]ethanol
  • 2-(1-benzhydrylazetidin-3-yl)propane-1,3-diol
  • 2-[2-(1,3-dioxolan-2-yl)ethyl]propane-1,3-diol
  • 2,2-bis[(4-phenyltriazol-1-yl)methyl]propane-1,3-diol
  • 2-(1,2,3,4-tetrahydroisoquinolin-1-yl)propane-1,3-diol
  • ethyl 2-((1H-indol-4-yl)amino)-2-oxoacetate
  • 4-(4-methoxyphenyl)-N-(1,3-thiazol-2-yl)-1,2,3-thiadiazole-5-carboxamide
  • 1H-1,2,4-Triazole-5-methanol, 3-[4-(1,1-dimethylethyl)phenyl]-
  • 3-(Butylethylamino)-2-butanone
  • 2-Methyl-5-[(2R)-2-pyrrolidinylmethoxy]pyridine
  • 5-Chloro-2-[(difluoromethyl)sulfanyl]aniline
  • N-cyclohexyl-4-(2,2,2-trifluoroethyl)piperazine-1-carboxamide
  • 2-(3-acetyl-1H-indol-1-yl)-N-(4-sulfamoylphenyl)acetamide
  • 5-(p-tolylamino)-1H-1,2,3-triazole-4-carboxamide
  • (2E)-3-(2-Chloro-5-methyl-3-pyridinyl)-2-propenenitrile
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