acetaminophen glucuronide sodium salt

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Names

[ CAS No. ]:
120595-80-4

[ Name ]:
acetaminophen glucuronide sodium salt

[Synonym ]:
MFCD00153898
ACETAMINOPHEN GLUCURONIDE SODIUM SALT
Acetaminophen glucuronide,Paracetamol glucuronide
Acetaminophen glucuronide Paracetamol glucuronide

Chemical & Physical Properties

[ Melting Point ]:
232-233ºC (dec)

[ Molecular Formula ]:
C14H16NNaO8

[ Molecular Weight ]:
349.27

[ Exact Mass ]:
349.07700

[ PSA ]:
148.38000

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Acetamidophenyl-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester
  • 2,3,4-Tri-O-acetyl-α-D-glucuronic Acid Methyl Ester
  • 3,4,6-TRI-O-ACETYL-ALPHA-D-GLUCOPYRANOSE 1,2-(METHYL ORTHOACETATE)

DownStream

Articles

Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition.

Drug Metab. Dispos. 43(1) , 147-53, (2014)

This study characterized the kinetics, variability, and factors that affect UDP-glucuronic acid (UDP-GlcUA) uptake by human liver microsomes (HLM). Biphasic kinetics were observed for UDP-GlcUA uptake...

Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater.

J. Pharm. Biomed. Anal. 106 , 61-70, (2015)

An analytical methodology for the simultaneous determination of seven pharmaceuticals and two metabolites belonging to the non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics therapeutic gro...

The effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite: paracetamol glucuronide.

Eur. J. Drug Metab. Pharmacokinet. 40 , 163-70, (2015)

The study aimed to examine the effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite, paracetamol glucuronide. Both drugs share metabolic pathways in the liver...


More Articles


Related Compounds

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  • propranolol glucuronide sodium salt
  • R-Licarbazepine Glucuronide Sodium Salt
  • d4-19-Norandrosterone glucuronide sodium salt
  • Estrone β-D-Glucuronide Sodium Salt
  • BetaMethasone β-D-Glucuronide SodiuM Salt
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
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  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine